2-allyl-2-phenylcyclopentanone

Base Information

• Chemical Name: 2-allyl-2-phenylcyclopentanone
• CAS No.: 106379-02-6
• Molecular Formula: C₁₄H₁₆O
• Molecular Weight: 200.28
• Mol file: 106379-02-6.mol

Synonyms:2-allyl-2-phenylcyclopentanone

Chemical Property of 2-allyl-2-phenylcyclopentanone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-allyl-2-phenylcyclopentanone

There total 11 articles about 2-allyl-2-phenylcyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

allyl 2-oxo-1-phenylcyclopentanecarboxylate → 2-allyl-2-phenylcyclopentanone (106379-02-6)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 1,2-bis-(diphenylphosphino)ethane; In 1,4-dioxane; at 40 ℃; for 5h; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201602250

Reference yield: 89.0%

2-Phenyl-2-(2-propenyl)-4-pentenecarboxaldehyde (171858-58-5) → 2-allyl-2-phenylcyclopentanone (106379-02-6) + 2-allyl-4-methyl-2-phenylcyclobutan-1-one + (2R,4R)-2-allyl-4-methyl-2-phenylcyclobutan-1-one

Guidance literature:

With Co[(S,S)-(S,S)-2,4-bis(diphenylphosphino)-pentane]Cl₂; diethylzinc; In acetonitrile; at 50 ℃; for 24h; Reagent/catalyst; regioselective reaction; Catalytic behavior; Glovebox; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.7b05327

Reference yield: 17.0%

2-Phenyl-2-(2-propenyl)-4-pentenecarboxaldehyde (171858-58-5) → 2-allyl-2-phenylcyclopentanone (106379-02-6) + 2-allyl-4-methyl-2-phenylcyclobutan-1-one

Guidance literature:

With (-)₅₈₉-2S-bis(diphenylphosphino)propane; cobalt(II) chloride; zinc; In acetonitrile; at 50 ℃; for 24h; Reagent/catalyst; regioselective reaction; Glovebox; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.7b05327

upstream raw materials:

2-Phenylcyclopentanone

3-chloroprop-1-ene

allyl 2-oxocyclopentane-1-carboxylate

phenylboronic acid

Downstream raw materials:

(1-phenyl-cyclopentyl)-acetaldehyde

3-(1-phenyl-cyclopentyl)-propane-1,2-diol

(1-phenyl-cyclopentyl)-acetic acid

1-Allyl-1-phenyl-cyclopentan