1-methyl-1H-indole-3-carboximidamide

Base Information

Chemical Name:1-methyl-1H-indole-3-carboximidamide
CAS No.:730237-52-2
Molecular Formula:C₁₀H₁₁N₃
Molecular Weight:173.217
Hs Code.:
DSSTox Substance ID:DTXSID50564283
Wikidata:Q82448944
Mol file:730237-52-2.mol

Synonyms:1-methyl-1H-indole-3-carboximidamide;730237-52-2;1-methylindole-3-carboximidamide;1-METHYLINDOLE-3-CARBOXAMIDINE;DTXSID50564283;AKOS006286852;EN300-1866050

Suppliers and Price of 1-methyl-1H-indole-3-carboximidamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-METHYLINDOLE-3-CARBOXAMIDINE 95.00%
5MG
$ 504.32

Total 8 raw suppliers

Chemical Property of 1-methyl-1H-indole-3-carboximidamide

Chemical Property:

PSA：54.80000
LogP:2.26240
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:173.095297364
Heavy Atom Count:13
Complexity:214

Purity/Quality:

99% ^*data from raw suppliers

1-METHYLINDOLE-3-CARBOXAMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=C(C2=CC=CC=C21)C(=N)N

Technology Process of 1-methyl-1H-indole-3-carboximidamide

There total 3 articles about 1-methyl-1H-indole-3-carboximidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 603-76-9
1-methylindole

: 420-04-2
CYANAMID

: 730237-52-2
1-methyl-1H-indole-3-carboxamidine

Guidance literature:: With 4,5-Diazafluoren-9-one; palladium(II) trifluoroacetate; toluene-4-sulfonic acid; In N,N-dimethyl acetamide; at 100 ℃; for 18h; Sealed tube;
DOI:10.1021/acs.orglett.7b01836

Reference yield:

: 125818-09-9
methyl 1-methyl-1H-indole-3-carboxamidate hydrochloride

: 730237-52-2
1-methyl-1H-indole-3-carboxamidine

: 118959-44-7
1-Methylindole-3-carboxylic acid amide

Guidance literature:: With ammonia; In methanol; for 24h; Title compound not separated from byproducts; Ambient temperature;
DOI:10.1021/jm00105a021

Reference yield:

: 24662-37-1
1-methyl-1H-indole-3-carbonitrile

: 730237-52-2
1-methyl-1H-indole-3-carboxamidine

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / hydrogen chloride (gas) / 24 h / Ambient temperature

2: ammonia (gas) / methanol / 24 h / Ambient temperature

With hydrogenchloride; ammonia; In methanol;
DOI:10.1021/jm00105a021