5-nitro-2-pyridin-2-ylbenzonitrile

Base Information

• Chemical Name: 5-nitro-2-pyridin-2-ylbenzonitrile
• CAS No.: 1021939-23-0
• Molecular Formula: C₁₂H₇N₃O₂
• Molecular Weight: 225.206
• Mol file: 1021939-23-0.mol

Synonyms:5-nitro-2-pyridin-2-ylbenzonitrile

Chemical Property of 5-nitro-2-pyridin-2-ylbenzonitrile

Chemical Property:

Purity/Quality:

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Technology Process of 5-nitro-2-pyridin-2-ylbenzonitrile

There total 1 articles about 5-nitro-2-pyridin-2-ylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-5-nitrobenzonitrile (134604-07-2) + pyridin-2-ylzinc(II) bromide → 5-nitro-2-pyridin-2-ylbenzonitrile (1021939-23-0)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 - 80 ℃; for 9h;

Reference yield:

5-nitro-2-pyridin-2-ylbenzonitrile (1021939-23-0) → 5-amino-2-pyridin-2-ylbenzonitrile (1021939-24-1)

Guidance literature:

With water; iron; ammonium chloride; In ethanol; for 1h; Heating / reflux;

upstream raw materials:

2-bromo-5-nitrobenzonitrile

Downstream raw materials:

5-amino-2-pyridin-2-ylbenzonitrile

Refernces