3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone

Base Information

Chemical Name:3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone
CAS No.:317334-71-7
Molecular Formula:C₂₁H₂₀N₂O
Molecular Weight:316.403
Hs Code.:

Synonyms:3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone

Suppliers and Price of 3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone

There total 5 articles about 3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 317334-69-3
(3-benzyl-5-bromophenyl)(5-methylpyrazin-2-yl)ketone

: 317334-71-7
3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrazine / ethylene glycol / 5 h / 110 °C

1.2: 4 h / 140 °C

2.1: -butyl vinyl ether; triethylamine / 1,3-bis-(diphenylphosphino)propane; palladium diacetate / DMF (N,N-dimethyl-formamide) / 100 °C

2.2: 3 h / 20 °C

With -butyl vinyl ether; triethylamine; hydrazine; 1,3-bis-(diphenylphosphino)propane; palladium diacetate; In DMF (N,N-dimethyl-formamide); ethylene glycol;

Reference yield:

: 51339-31-2
3,5-dibromo-benzhydrol

: 317334-71-7
3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 20 °C

2.1: n-butyllithium / hexanes; diethyl ether / 1 h / -78 °C

2.2: -78 - 20 °C

3.1: hydrazine / ethylene glycol / 5 h / 110 °C

3.2: 4 h / 140 °C

4.1: -butyl vinyl ether; triethylamine / 1,3-bis-(diphenylphosphino)propane; palladium diacetate / DMF (N,N-dimethyl-formamide) / 100 °C

4.2: 3 h / 20 °C

With triethylsilane; n-butyllithium; -butyl vinyl ether; boron trifluoride diethyl etherate; triethylamine; hydrazine; 1,3-bis-(diphenylphosphino)propane; palladium diacetate; In hexanes; DMF (N,N-dimethyl-formamide); diethyl ether; dichloromethane; ethylene glycol;

Reference yield:

: 626-39-1
1,3,5-trisbromobenzene

: 317334-71-7
3-benzyl-5-(5-methylpyrazin-2-yl)methylacetophenone

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / hexanes; diethyl ether / 0.5 h / -78 °C

1.2: -78 - 0 °C

2.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 20 °C

3.1: n-butyllithium / hexanes; diethyl ether / 1 h / -78 °C

3.2: -78 - 20 °C

4.1: hydrazine / ethylene glycol / 5 h / 110 °C

4.2: 4 h / 140 °C

5.1: -butyl vinyl ether; triethylamine / 1,3-bis-(diphenylphosphino)propane; palladium diacetate / DMF (N,N-dimethyl-formamide) / 100 °C

5.2: 3 h / 20 °C

With triethylsilane; n-butyllithium; -butyl vinyl ether; boron trifluoride diethyl etherate; triethylamine; hydrazine; 1,3-bis-(diphenylphosphino)propane; palladium diacetate; In hexanes; DMF (N,N-dimethyl-formamide); diethyl ether; dichloromethane; ethylene glycol;