Methyl 5-oxo-4,5,6,7-tetrahydropyrazolo[1,5-A]pyridine-3-carboxylate

Base Information

Chemical Name:Methyl 5-oxo-4,5,6,7-tetrahydropyrazolo[1,5-A]pyridine-3-carboxylate
CAS No.:866216-24-2
Molecular Formula:C₉H₁₀N₂O₃
Molecular Weight:194.19
Hs Code.:
DSSTox Substance ID:DTXSID40468867
Wikidata:Q82296319
Mol file:866216-24-2.mol

Synonyms:866216-24-2;METHYL 5-OXO-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE;Pyrazolo[1,5-a]pyridine-3-carboxylicacid, 4,5,6,7-tetrahydro-5-oxo-, methyl ester;methyl 5-oxo-6,7-dihydro-4H-pyrazolo[1,5-a]pyridine-3-carboxylate;METHYL 5-OXO-4H,5H,6H,7H-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE;DTXSID40468867;AKOS006285252;AB44570

Suppliers and Price of Methyl 5-oxo-4,5,6,7-tetrahydropyrazolo[1,5-A]pyridine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL-5-OXO-4,5,6,7-TETRAHYDROPYRAZOLO-[1,5-A]-PYRIDINE-3-CARBOXYLATE 95.00%
5MG
$ 500.40

Total 5 raw suppliers

Chemical Property of Methyl 5-oxo-4,5,6,7-tetrahydropyrazolo[1,5-A]pyridine-3-carboxylate

Chemical Property:

PSA：61.19000
LogP:0.18500
XLogP3:-0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:194.06914219
Heavy Atom Count:14
Complexity:267

Purity/Quality:

98%min ^*data from raw suppliers

METHYL-5-OXO-4,5,6,7-TETRAHYDROPYRAZOLO-[1,5-A]-PYRIDINE-3-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C2CC(=O)CCN2N=C1

Technology Process of Methyl 5-oxo-4,5,6,7-tetrahydropyrazolo[1,5-A]pyridine-3-carboxylate

There total 4 articles about Methyl 5-oxo-4,5,6,7-tetrahydropyrazolo[1,5-A]pyridine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 866216-23-1
methyl 5-hydroxy-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-3-carboxylate

: 866216-24-2
methyl 5-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-3-carboxylate

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm0503805

Reference yield:

: 866216-17-3
methyl 5-benzyloxypyrazolo[1,5-a]pyridine-3-carboxylate

: 866216-24-2
methyl 5-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / H₂ / Pd/C / ethanol / 48 h / 80 °C / 15001.2 Torr

2: 70 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 20 °C

With hydrogen; Dess-Martin periodane; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/jm0503805

Reference yield:

: N-amino-4-benzyloxypyridinium mesitylenesulfonate

: 866216-24-2
methyl 5-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 6.3 g / K₂CO₃ / dimethylformamide / 16 h / 20 °C

2: 75 percent / H₂ / Pd/C / ethanol / 48 h / 80 °C / 15001.2 Torr

3: 70 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 20 °C

With hydrogen; potassium carbonate; Dess-Martin periodane; palladium on activated charcoal; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm0503805