Technology Process of C33H51N7O8
There total 4 articles about C33H51N7O8 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-{[(benzyloxy)carbonyl]amino}cyclohexanecarboxylic acid;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
at 0 ℃;
Inert atmosphere;
GlyNH2-Aib4-NH2;
In
dichloromethane;
at 0 - 20 ℃;
for 48h;
Inert atmosphere;
DOI:10.1039/c2cc00060a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / acetonitrile / 72 h / Inert atmosphere
2.1: palladium on activated charcoal; hydrogen / methanol
3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C / Inert atmosphere
3.2: 48 h / 0 - 20 °C / Inert atmosphere
With
palladium on activated charcoal; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
methanol; dichloromethane; acetonitrile;
DOI:10.1039/c2cc00060a
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: acetic anhydride / 2 h / 120 °C / Inert atmosphere
2.1: triethylamine / acetonitrile / 72 h / Inert atmosphere
3.1: palladium on activated charcoal; hydrogen / methanol
4.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 °C / Inert atmosphere
4.2: 48 h / 0 - 20 °C / Inert atmosphere
With
palladium on activated charcoal; hydrogen; acetic anhydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
methanol; dichloromethane; acetonitrile;
DOI:10.1039/c2cc00060a
