(2R,3R)-2-(benzylthio)-3-(2,5-dioxopyrrolidin-1-yl)-3-(naphthalen-2-yl)propanal

Base Information

• Chemical Name: (2R,3R)-2-(benzylthio)-3-(2,5-dioxopyrrolidin-1-yl)-3-(naphthalen-2-yl)propanal
• CAS No.: 1095532-16-3
• Molecular Formula: C₂₄H₂₁NO₃S
• Molecular Weight: 403.502
• Mol file: 1095532-16-3.mol

Synonyms:(2R,3R)-2-(benzylthio)-3-(2,5-dioxopyrrolidin-1-yl)-3-(naphthalen-2-yl)propanal

Chemical Property of (2R,3R)-2-(benzylthio)-3-(2,5-dioxopyrrolidin-1-yl)-3-(naphthalen-2-yl)propanal

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (2R,3R)-2-(benzylthio)-3-(2,5-dioxopyrrolidin-1-yl)-3-(naphthalen-2-yl)propanal

There total 1 articles about (2R,3R)-2-(benzylthio)-3-(2,5-dioxopyrrolidin-1-yl)-3-(naphthalen-2-yl)propanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(naphthalen-2-yl)prop-2-en-1-al (113388-98-0,20884-05-3) + N-(benzylthio)succinimide (14204-23-0) → (2R,3R)-2-(benzylthio)-3-(2,5-dioxopyrrolidin-1-yl)-3-(naphthalen-2-yl)propanal (1095532-16-3) + (2S,3R)-2-(benzylthio)-3-(2,5-dioxopyrrolidin-1-yl)-3-(naphthalen-2-yl)propanal (1095532-15-2)

Guidance literature:

With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; Succinimide; In chloroform; at 20 ℃; for 16h; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/anie.200802335

upstream raw materials:

3-(naphthalen-2-yl)prop-2-en-1-al

N-(benzylthio)succinimide