(1S,2S)-1-(3',4'-bis(benzyloxy)phenyl)-3-(2-tert-butylthiophenyl)propane-1,2-diol

Base Information

• Chemical Name: (1S,2S)-1-(3',4'-bis(benzyloxy)phenyl)-3-(2-tert-butylthiophenyl)propane-1,2-diol
• CAS No.: 1239335-37-5
• Molecular Formula: C₃₃H₃₆O₄S
• Molecular Weight: 528.712
• Mol file: 1239335-37-5.mol

Synonyms:(1S,2S)-1-(3',4'-bis(benzyloxy)phenyl)-3-(2-tert-butylthiophenyl)propane-1,2-diol

Chemical Property of (1S,2S)-1-(3',4'-bis(benzyloxy)phenyl)-3-(2-tert-butylthiophenyl)propane-1,2-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (1S,2S)-1-(3',4'-bis(benzyloxy)phenyl)-3-(2-tert-butylthiophenyl)propane-1,2-diol

There total 1 articles about (1S,2S)-1-(3',4'-bis(benzyloxy)phenyl)-3-(2-tert-butylthiophenyl)propane-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

(E)-2-(3-(3',4'-bis(benzyloxy)phenyl)allyl)phenyl-tert-butylsulfane (1239335-36-4) → (1S,2S)-1-(3',4'-bis(benzyloxy)phenyl)-3-(2-tert-butylthiophenyl)propane-1,2-diol (1239335-37-5)

Guidance literature:

(E)-2-(3-(3',4'-bis(benzyloxy)phenyl)allyl)phenyl-tert-butylsulfane; With AD-mix-α; In dichloromethane; water; tert-butyl alcohol; at 0 ℃;

With methanesulfonamide; In dichloromethane; water; tert-butyl alcohol; at 0 ℃; for 24h; optical yield given as %ee;

DOI:10.3390/molecules15085595

Reference yield: 68.0%

(1S,2S)-1-(3',4'-bis(benzyloxy)phenyl)-3-(2-tert-butylthiophenyl)propane-1,2-diol (1239335-37-5) → 3',4'-bis(benzyloxy)-5,7-dideoxy-(+)-thioepicatechin (1239335-39-7) + 3',4'-bis(benzyloxy)-5,7-dideoxy-(+)-thiocatechin (1239335-38-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 5 ℃;

DOI:10.3390/molecules15085595

upstream raw materials:

(E)-2-(3-(3',4'-bis(benzyloxy)phenyl)allyl)phenyl-tert-butylsulfane

Downstream raw materials:

3',4'-bis(benzyloxy)-5,7-dideoxy-(+)-thioepicatechin

3',4'-bis(benzyloxy)-5,7-dideoxy-(+)-thiocatechin