Fmoc-Asn-ONp

Base Information

• Chemical Name: Fmoc-Asn-ONp
• CAS No.: 71989-17-8
• Molecular Formula: C25H21 N3 O7
• Molecular Weight: 475.45
• DSSTox Substance ID: DTXSID90548946
• Wikidata: Q82427810
• Mol file: 71989-17-8.mol

Synonyms:Fmoc-Asn-ONp;71989-17-8;(S)-4-Nitrophenyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-amino-4-oxobutanoate;(4-nitrophenyl) (2S)-4-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxobutanoate;C25H21N3O7;DTXSID90548946;MFCD00063329;AKOS016014009;Fmoc-L-asparagine 4-nitrophenyl ester;FD21198;AS-48995;CS-0360475;9-fluorenylmethyloxycarbonyl-l-asparagine p-nitrophenyl ester;4-Nitrophenyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-asparaginate;4-Nitrophenyl N~2~-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-asparaginate;L-Asparagine,n2-[(9H-fluoren-9-ylmethoxy)carbonyl]-,4-nitrophenyl ester;(S)-4-nitrophenyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-amino-4-oxobutanoate;(S)-4-Nitrophenyl2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-amino-4-oxobutanoate

Chemical Property of Fmoc-Asn-ONp

Chemical Property:

• Vapor Pressure: 3.28E-24mmHg at 25°C
• Melting Point: 184-188 °C
• Boiling Point: 779°C at 760 mmHg
• PKA: 9.94±0.46(Predicted)
• Flash Point: 424.9°C
• PSA: 153.54000
• Density: 1.387g/cm³
• LogP: 4.89730
• Storage Temp.: 2-8°C
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 9
• Exact Mass: 475.13795002
• Heavy Atom Count: 35
• Complexity: 770

Purity/Quality:

99% ^*data from raw suppliers

FMOC-ASN-ONP ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC(=O)N)C(=O)OC4=CC=C(C=C4)[N+](=O)[O-]
• Isomeric SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CC(=O)N)C(=O)OC4=CC=C(C=C4)[N+](=O)[O-]

Technology Process of Fmoc-Asn-ONp

There total 1 articles about Fmoc-Asn-ONp which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + Fmoc-Asn-OH (71989-16-7) → Nα-fluorenylmethoxycarbonyl-L-asparagine p-nitrophenyl ester (71989-17-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In ethyl acetate; at 0 ℃;

DOI:10.1021/jo01289a016

upstream raw materials:

4-nitro-phenol

Fmoc-Asn-OH