(6-hydroxynaphthalen-2-yl)boronic Acid

Base Information

Chemical Name:(6-hydroxynaphthalen-2-yl)boronic Acid
CAS No.:173194-95-1
Molecular Formula:C10H9BO3
Molecular Weight:187.991
Hs Code.:29319090
European Community (EC) Number:687-349-8
DSSTox Substance ID:DTXSID60402228
Wikidata:Q72480575
Mol file:173194-95-1.mol

Synonyms:173194-95-1;6-Hydroxy-2-naphthaleneboronic acid;(6-hydroxynaphthalen-2-yl)boronic Acid;6-Hydroxynaphthalene-2-boronic acid;6-hydroxynaphthalen-2-ylboronic acid;(6-HYDROXY-2-NAPHTHYL)BORONIC ACID;MFCD00092986;Boronic acid, (6-hydroxy-2-naphthalenyl)-;EC 687-349-8;6-Hydroxyl-2-naphthaleneboronicacid;6-HYDROXY-2-NAPHTHYLENEBORONIC ACID;C10H9BO3;Boronic acid,B-(6-hydroxy-2-naphthalenyl)-;5-Naphthol-1-boronic acid;SCHEMBL8649;DTXSID60402228;6-Hydroxy-2-naphthylboronic Acid;SNJANQMHRGSHFN-UHFFFAOYSA-N;6-Hydroxy-2-naphthaleneboronicacid;AMY13270;YGA19495;BBL102137;STL555936;6-hydroxynaphthalen-2-yl boronic acid;AKOS004119221;AB03326;CS-W000884;(6-hydroxy-2-naphthalenyl)boronic acid;AC-28132;AS-18696;SY021651;FT-0643656;H1402;Boronic acid, B-(6-hydroxy-2-naphthalenyl)-;EN300-212492;6-hydroxy-2-naphthaleneboronic acid, AldrichCPR;A811494;J-518796;Z1201619060;(6-hydroxy-2-naphthyl)boronic acid;(6-Hydroxynaphthalen-2-yl)boronic acid

Suppliers and Price of (6-hydroxynaphthalen-2-yl)boronic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Hydroxynaphthalene-2-boronicAcid
1g
$ 250.00

TCI Chemical
6-Hydroxy-2-naphthaleneboronic Acid (contains varying amounts of Anhydride)
5g
$ 160.00

TCI Chemical
6-Hydroxy-2-naphthaleneboronic Acid (contains varying amounts of Anhydride)
1g
$ 54.00

Synthonix
(6-Hydroxynaphthalen-2-yl)boronicacid 98%
25g
$ 890.00

Synthonix
(6-Hydroxynaphthalen-2-yl)boronicacid 98%
5g
$ 60.00

Synthonix
(6-Hydroxynaphthalen-2-yl)boronicacid 98%
100mg
$ 15.00

Synthonix
(6-Hydroxynaphthalen-2-yl)boronicacid 98%
1g
$ 25.00

Synthonix
(6-Hydroxynaphthalen-2-yl)boronicacid 98%
250mg
$ 20.00

Synthonix
(6-Hydroxynaphthalen-2-yl)boronicacid 98%
10g
$ 90.00

Matrix Scientific
(6-Hydroxynaphthalen-2-yl)boronic acid 98%
1g
$ 100.00

Total 88 raw suppliers

Chemical Property of (6-hydroxynaphthalen-2-yl)boronic Acid

Chemical Property:

Vapor Pressure:3.33E-09mmHg at 25°C
Melting Point:218-224 °C
Refractive Index:1.681
Boiling Point:458.567 °C at 760 mmHg
PKA:8.80±0.30(Predicted)
Flash Point:231.134 °C
PSA：60.69000
Density:1.358 g/cm³
LogP:0.22520
Storage Temp.:Keep Cold
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:188.0644743
Heavy Atom Count:14
Complexity:198

Purity/Quality:

98% ^*data from raw suppliers

6-Hydroxynaphthalene-2-boronicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC2=C(C=C1)C=C(C=C2)O)(O)O
Uses 6-Hydroxynaphthalene-2-boronic acid can be used to synthesize inhibitors for oxygenase, tyrosine and phosphoinositide kinases. Tyrosine and phosphoinositide kinases are an attractive target for developing cancer drugs.

Technology Process of (6-hydroxynaphthalen-2-yl)boronic Acid

There total 1 articles about (6-hydroxynaphthalen-2-yl)boronic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 15231-91-1
6-bromo-naphthalen-2-ol

: 173194-95-1
(6-hydroxynaphthalen-2-yl)boronic acid

Guidance literature:: 6-bromo-naphthalen-2-ol; With n-butyllithium; In tetrahydrofuran; hexane; at -70 ℃; for 2h; Inert atmosphere;

With Triisopropyl borate; In tetrahydrofuran; hexane; at -70 - 20 ℃; for 3.5h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; hexane; water; at 20 ℃; for 2h;

Reference yield: 82.0%

: 173194-95-1
(6-hydroxynaphthalen-2-yl)boronic acid

: 942154-19-0
1-(3-bromobenzyl)-1H-1,2,4-triazole

: 6-(3-(1H-1,2,4-triazol-1-ylmethyl)phenyl)naphthalen-2-ol

Guidance literature:: With tetrabutylammomium bromide; potassium carbonate; palladium diacetate; In ethanol; water; at 150 ℃; for 0.166667h; Irradiation;

Reference yield: 73.0%

: 173194-95-1
(6-hydroxynaphthalen-2-yl)boronic acid

: N-(2-bromophenyl)-3',6-dimethoxy-[1,1'-biphenyl]-3-carboxamide

: N-(2-(6-hydroxynaphthalen-2-yl)phenyl)-3',6-dimethoxy-[1,1'-biphenyl]-3-carboxamide

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; In water; N,N-dimethyl-formamide; at 130 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/chem.201504955