trimethoxy(m-tolyl)silane

Base Information

• Chemical Name: trimethoxy(m-tolyl)silane
• CAS No.: 35692-20-7
• Molecular Formula: C₁₀H₁₆O₃Si
• Molecular Weight: 212.321
• Mol file: 35692-20-7.mol

Synonyms:trimethoxy(m-tolyl)silane

Chemical Property of trimethoxy(m-tolyl)silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of trimethoxy(m-tolyl)silane

There total 1 articles about trimethoxy(m-tolyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetramethylorthosilicate (681-84-5) → trimethoxy(m-tolyl)silane (35692-20-7)

Guidance literature:

In tetrahydrofuran; at -30 - 20 ℃; for 13h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c00631

Reference yield: 93.0%

trimethoxy(m-tolyl)silane (35692-20-7) + N,N,N-trimethyl-1-(4-cyanophenyl)methanaminium trifluoromethanesulfonate → 4-(3-methyl-benzyl)-benzonitrile (1235271-47-2)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); tetrabutyl ammonium fluoride; cyclohexyldiphenylphosphine; In ethanol; at 120 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.joc.9b02554

Reference yield: 91.0%

cyclohexenone (930-68-7) + trimethoxy(m-tolyl)silane (35692-20-7) → 3'-methyl-5,6-dihydro[1,1'-biphenyl]-3(4H)-one (82942-79-8)

Guidance literature:

With 1,10-Phenanthroline; palladium diacetate; silver fluoride; In N,N-dimethyl-formamide; at 60 ℃;

DOI:10.1055/s-0029-1217571

upstream raw materials:

tetramethylorthosilicate

Downstream raw materials:

1-m-tolyl-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undecan-3-one

1,2-diphenyl-1-m-tolyl-ethene

N-(3-m-tolyl-2H-chromen-4-yl)acetamide

3-Methyldiphenylamine

Refernces

• 1、 Lu, Ming-Zhu,Loh, Teck-Peng,Luo, Haiqing,Hu, Zhengsong,Shao, Changdong,Kan, Yuhe. "Directed palladium(II)-catalyzed intermolecular anti-markovnikov hydroarylation of unactivated alkenes with (hetero)arylsilanes". supporting information. p. 9022 - 9028. Retrieved 2020/12/02.