tetrahydro-3-(2-oxo-2-phenylethyl)-2-(phenylimino)-3-furancarbonitrile

Base Information

• Chemical Name: tetrahydro-3-(2-oxo-2-phenylethyl)-2-(phenylimino)-3-furancarbonitrile
• CAS No.: 1017244-05-1
• Molecular Formula: C₁₉H₁₆N₂O₂
• Molecular Weight: 304.348
• Mol file: 1017244-05-1.mol

Synonyms:tetrahydro-3-(2-oxo-2-phenylethyl)-2-(phenylimino)-3-furancarbonitrile

Chemical Property of tetrahydro-3-(2-oxo-2-phenylethyl)-2-(phenylimino)-3-furancarbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of tetrahydro-3-(2-oxo-2-phenylethyl)-2-(phenylimino)-3-furancarbonitrile

There total 1 articles about tetrahydro-3-(2-oxo-2-phenylethyl)-2-(phenylimino)-3-furancarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

4,5-dihydro-2-(phenylamino)-3-furancarbonitrile (1017243-99-0) + α-bromoacetophenone (70-11-1) → tetrahydro-3-(2-oxo-2-phenylethyl)-2-(phenylimino)-3-furancarbonitrile (1017244-05-1)

Guidance literature:

4,5-dihydro-2-(phenylamino)-3-furancarbonitrile; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃;

α-bromoacetophenone; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Further stages.;

DOI:10.3987/com-07-s(w)16

Reference yield: 95.0%

tetrahydro-3-(2-oxo-2-phenylethyl)-2-(phenylimino)-3-furancarbonitrile (1017244-05-1) → 2-oxo-3-(2-oxo-2-phenylethyl)-1-phenyl-3-pyrrolidinecarbonitrile (1017244-30-2)

Guidance literature:

With sodium iodide; In N,N-dimethyl-formamide; at 150 ℃; for 2h;

DOI:10.3987/com-07-s(w)16

Reference yield: 85.0%

tetrahydro-3-(2-oxo-2-phenylethyl)-2-(phenylimino)-3-furancarbonitrile (1017244-05-1) → 3-cyano-2-oxo-3-phenacyltetrahydrofuran

Guidance literature:

With hydrogenchloride; at 20 ℃; for 20h;

DOI:10.3987/com-07-s(w)16

upstream raw materials:

4,5-dihydro-2-(phenylamino)-3-furancarbonitrile

α-bromoacetophenone

Downstream raw materials:

2-oxo-3-(2-oxo-2-phenylethyl)-1-phenyl-3-pyrrolidinecarbonitrile