4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester

Base Information

Chemical Name:4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester
CAS No.:1262328-59-5
Molecular Formula:C₂₀H₁₆F₃NO₆S
Molecular Weight:455.411
Hs Code.:

Synonyms:4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester

Suppliers and Price of 4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester

There total 3 articles about 4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 873927-78-7
4-[4-(2,4-dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester

: 1262328-59-5
4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester

Guidance literature:: With sodium tetrahydroborate; cobalt(II) chloride hexahydrate; butane-2,3-dione dioxime; sodium hydroxide; In tetrahydrofuran; water; N,N-dimethyl-formamide; at 20 ℃; Cooling with ice;
DOI:10.1021/jm101063h

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 1262328-59-5
4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 95 °C

2: ammonium acetate; acetic acid / 100 °C

3: sodium tetrahydroborate; cobalt(II) chloride hexahydrate; butane-2,3-dione dioxime; sodium hydroxide / tetrahydrofuran; water; N,N-dimethyl-formamide / 20 °C / Cooling with ice

With sodium tetrahydroborate; cobalt(II) chloride hexahydrate; ammonium acetate; potassium carbonate; acetic acid; butane-2,3-dione dioxime; sodium hydroxide; In tetrahydrofuran; water; N,N-dimethyl-formamide; 2: Knoevenagel condensation;
DOI:10.1021/jm101063h

Reference yield:

: 220141-23-1
4-Fluoro-2-trifluoromethylbenzoic acid methyl ester

: 1262328-59-5
4-[4-(2,4-dioxothiazolidin-5-ylmethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 95 °C

2: ammonium acetate; acetic acid / 100 °C

3: sodium tetrahydroborate; cobalt(II) chloride hexahydrate; butane-2,3-dione dioxime; sodium hydroxide / tetrahydrofuran; water; N,N-dimethyl-formamide / 20 °C / Cooling with ice

With sodium tetrahydroborate; cobalt(II) chloride hexahydrate; ammonium acetate; potassium carbonate; acetic acid; butane-2,3-dione dioxime; sodium hydroxide; In tetrahydrofuran; water; N,N-dimethyl-formamide; 2: Knoevenagel condensation;
DOI:10.1021/jm101063h