3-BROMO-4-NITROBENZOIC ACID 97

Base Information

• Chemical Name: 3-BROMO-4-NITROBENZOIC ACID 97
• CAS No.: 101420-81-9
• Molecular Formula: C7H4BrNO4
• Molecular Weight: 246.017
• Hs Code.: 2916399090
• Mol file: 101420-81-9.mol

Synonyms:4-Nitro-3-bromobenzoic acid;

Chemical Property of 3-BROMO-4-NITROBENZOIC ACID 97

Chemical Property:

• Melting Point: 200-204 °C
• Boiling Point: 364.43 °C at 760 mmHg
• PKA: 3.03±0.10(Predicted)
• Flash Point: 174.202 °C
• PSA: 83.12000
• Density: 1.893 g/cm³
• LogP: 2.57870
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: soluble in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Bromo-4-nitrobenzoic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Substrate linked to a solid support via the carboxyl group which is used in a Bartoli synthesis of indoles.

Technology Process of 3-BROMO-4-NITROBENZOIC ACID 97

There total 6 articles about 3-BROMO-4-NITROBENZOIC ACID 97 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-benzoic acid (62-23-7) → 3-Bromo-4-nitrobenzoic acid (101420-81-9)

Guidance literature:

With carbon disulfide; bromine; at 35 ℃; for 2h; under 6000.6 Torr; Temperature; Pressure;

Reference yield:

3-bromo-4-nitrotoluene (40385-54-4) → 3-Bromo-4-nitrobenzoic acid (101420-81-9)

Guidance literature:

With chromium(VI) oxide; acetic acid;

DOI:10.1021/ja01157a007

Reference yield:

3-bromo-4-nitrobenzonitrile (102000-73-7) → 3-Bromo-4-nitrobenzoic acid (101420-81-9)

Guidance literature:

With sulfuric acid;

upstream raw materials:

3-bromo-4-nitrotoluene

3-bromo-4-nitrobenzonitrile

3-bromoacetanilide

3-bromo-4-nitroaniline

Downstream raw materials:

3-bromo-4-nitro-benzoyl chloride

N-(2-Nitro-5-carboxy-phenyl)-DL-α-alanin-diaethylester

3-methoxy-4-nitrobenzoic acid

N-(2-Nitro-5-carboxy-phenyl)-DL-α-alanin

Refernces

• 1、 -. "3-methoxy-4-nitrobenzoic acid and preparation method thereof". Paragraph 0016; 0017; 0018. . Retrieved 2016/10/10.