3-Hydroxy-1-[2-(4-nitro-phenyl)-ethyl]-1-azonia-bicyclo[2.2.2]octane; perchlorate

Base Information

• Chemical Name: 3-Hydroxy-1-[2-(4-nitro-phenyl)-ethyl]-1-azonia-bicyclo[2.2.2]octane; perchlorate
• CAS No.: 83967-66-2
• Molecular Formula: C₁₅H₂₁N₂O₃*ClO₄
• Molecular Weight: 376.794
• Mol file: 83967-66-2.mol

Synonyms:3-Hydroxy-1-[2-(4-nitro-phenyl)-ethyl]-1-azonia-bicyclo[2.2.2]octane; perchlorate

Chemical Property of 3-Hydroxy-1-[2-(4-nitro-phenyl)-ethyl]-1-azonia-bicyclo[2.2.2]octane; perchlorate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Hydroxy-1-[2-(4-nitro-phenyl)-ethyl]-1-azonia-bicyclo[2.2.2]octane; perchlorate

There total 1 articles about 3-Hydroxy-1-[2-(4-nitro-phenyl)-ethyl]-1-azonia-bicyclo[2.2.2]octane; perchlorate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(4-nitrophenyl)ethyl bromide (5339-26-4) + 3-RS-quinuclidinol hydrochloride (6238-13-7) → 3-Hydroxy-1-[2-(4-nitro-phenyl)-ethyl]-1-azonia-bicyclo[2.2.2]octane; perchlorate (83967-66-2)

Guidance literature:

With sodium hydroxide; perchloric acid; 1.) MeOH, 24 h, RT, 2.) H₂O;

DOI:10.1021/ja00340a021

Reference yield:

3-Hydroxy-1-[2-(4-nitro-phenyl)-ethyl]-1-azonia-bicyclo[2.2.2]octane; perchlorate (83967-66-2) → 4-nitrostyrene (100-13-0)

Guidance literature:

With acetohydroxamate buffer; potassium chloride; In water; at 25 ℃; Rate constant; Mechanism; also with KOH or acetohydroxamic acid;

DOI:10.1021/ja00340a021

upstream raw materials:

(4-nitrophenyl)ethyl bromide

3-RS-quinuclidinol hydrochloride

Downstream raw materials:

4-nitrostyrene