BOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID

Base Information

Chemical Name:BOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID
CAS No.:73397-26-9
Molecular Formula:C₁₂H₂₃NO₅
Molecular Weight:261.318
Hs Code.:2924199090
Mol file:73397-26-9.mol

Synonyms:N-BOC-(2R,3R)-2-HYDROXY-3-AMINO-5-METHYLHEXANOIC ACID;(2R,3R)-3-BOC-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID;BOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID;BOC-(2R,3R)-AHMH-OH

Suppliers and Price of BOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
N-Boc-(2R,3R)-2-hydroxy-3-amino-5-methylhexanoicacid
1 g
$ 695.00

Matrix Scientific
Boc-(2R,3R)-3-amino-2-hydroxy-5-methylhexanoic acid
1g
$ 763.00

Matrix Scientific
Boc-(2R,3R)-3-amino-2-hydroxy-5-methylhexanoic acid
100mg
$ 179.00

Matrix Scientific
Boc-(2R,3R)-3-amino-2-hydroxy-5-methylhexanoic acid
500mg
$ 555.00

Crysdot
(2R,3R)-3-((tert-Butoxycarbonyl)amino)-2-hydroxy-5-methylhexanoicacid 95+%
1g
$ 472.00

American Custom Chemicals Corporation
(2R,3R)-3-BOC-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID 95.00%
5G
$ 2656.50

American Custom Chemicals Corporation
(2R,3R)-3-BOC-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID 95.00%
1G
$ 1033.73

AK Scientific
Boc-(2R,3R)-3-amino-2-hydroxy-5-methylhexanoicacid
500mg
$ 799.00

AK Scientific
Boc-(2R,3R)-3-amino-2-hydroxy-5-methylhexanoicacid
100mg
$ 291.00

Total 18 raw suppliers

Chemical Property of BOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID

Chemical Property:

PSA：95.86000
LogP:1.76220

Purity/Quality:

99% ^*data from raw suppliers

N-Boc-(2R,3R)-2-hydroxy-3-amino-5-methylhexanoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of BOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID

There total 14 articles about BOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 73397-30-5
(2R,3R)-3-<<(tert-Butyloxy)carbonyl>amino>-2-hydroxy-5-methylhexanoic Acid Methyl Ester

: 73397-26-9
(2R,3R)-3-<<(tert-Butyloxy)carbonyl>amino>-2-hydroxy-5-methylhexanoic Acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; pH 10;
DOI:10.1021/jo01300a004

Reference yield: 73.0%

: 1070-19-5
N-(tert-butyloxycarbonyl) azide

: 62023-30-7,70853-11-1,70853-17-7,73397-20-3,73397-21-4,75556-30-8
(2RS,3R)-3-Amino-2-hydroxy-5-methylhexanoic Acid

: 73397-25-8,73397-26-9,73397-27-0,73397-28-1,77119-88-1
(2RS,3R)-3-<<(tert-Butyloxy)carbonyl>amino>-2-hydroxy-5-methylhexanoic Acid

Guidance literature:: With triethylamine; In 1,4-dioxane; water; at 25 ℃;
DOI:10.1021/jo01300a004

Reference yield:

: 70853-26-8
(R)-4-methyl-1-oxopentane-2-benzylcarbamate

: 73397-25-8,73397-26-9,73397-27-0,73397-28-1,77119-88-1
(2RS,3R)-3-<<(tert-Butyloxy)carbonyl>amino>-2-hydroxy-5-methylhexanoic Acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaHSO₃ / 1.) 5 deg C, overnight, 2.) ethyl acetate, water, room temp., 4 h

2: 90 percent / concentrated HCl / dioxane / 12 h / Heating

3: 73 percent / triethylamine / H₂O; dioxane / 25 °C

With hydrogenchloride; sodium hydrogensulfite; triethylamine; In 1,4-dioxane; water;
DOI:10.1021/jo01300a004