(5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylidene)-1,3-thiazol-4(5H)-one

Base Information

Chemical Name:(5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylidene)-1,3-thiazol-4(5H)-one
CAS No.:1025821-33-3
Molecular Formula:C₁₈H₁₀Cl₂N₄OS
Molecular Weight:401.276
Hs Code.:

Synonyms:(5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylidene)-1,3-thiazol-4(5H)-one

Suppliers and Price of (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylidene)-1,3-thiazol-4(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
GSK-626616
10mg
$ 160.00

Tocris
GSK626616 ≥98%(HPLC)
50
$ 861.00

Tocris
GSK626616 ≥98%(HPLC)
10
$ 205.00

ChemScene
GSK-626616 99.83%
10mg
$ 270.00

ChemScene
GSK-626616 99.83%
5mg
$ 160.00

ChemScene
GSK-626616 99.83%
100mg
$ 1350.00

ChemScene
GSK-626616 99.83%
50mg
$ 800.00

Biosynth Carbosynth
GSK 626616 NEW
50 mg
$ 472.50

Biosynth Carbosynth
GSK 626616 NEW
10 mg
$ 135.00

AK Scientific
4(5H)-Thiazolone,2-((2,6-dichlorophenyl)amino)-5-(6-quinoxalinylmethylene)-,(5Z)-
10mg
$ 232.00

Total 9 raw suppliers

Chemical Property of (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylidene)-1,3-thiazol-4(5H)-one

Chemical Property:

Melting Point:281 - 282oC
Boiling Point:574.8±60.0 °C(Predicted)
Density:1.55±0.1 g/cm3(Predicted)

Purity/Quality:

>98 % ^*data from raw suppliers

GSK-626616 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses GSK-626616 is a potent and selective DYRK inhibitor (IC50 = 0.7 nM for DYRK3, similar potency for DYRK1 and 2). Exhibits ~20-fold selectivity over casein kinase 2 and negligible activity against a panel of 451 kinases screened. Enhances number of CFU-E stimulated by Epo from human marrow. Increases hemoglobin levels in anemic mice. Orally bioavailable.

Technology Process of (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylidene)-1,3-thiazol-4(5H)-one

There total 1 articles about (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylidene)-1,3-thiazol-4(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%