4-methylstyrenylboronic acid

Base Information

• Chemical Name: 4-methylstyrenylboronic acid
• CAS No.: 214907-11-6
• Molecular Formula: C₉H₁₁BO₂
• Molecular Weight: 161.996
• Mol file: 214907-11-6.mol

Synonyms:4-methylstyrenylboronic acid

Chemical Property of 4-methylstyrenylboronic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-methylstyrenylboronic acid

There total 5 articles about 4-methylstyrenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-n-methylphenylacetylene (766-97-2) + benzo[1,3,2]dioxaborole (274-07-7) → 4-methylstyrenylboronic acid (214907-11-6)

Guidance literature:

4-n-methylphenylacetylene; benzo[1,3,2]dioxaborole; In tetrahydrofuran; at 65 ℃; for 24h;

With water; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/acs.orglett.8b02234

Reference yield:

4,4,5,5-tetramethyl-2-(2-p-tolylvinyl)[1,3,2]dioxaborolane (1377187-54-6) → 4-methylstyrenylboronic acid (214907-11-6)

Guidance literature:

4,4,5,5-tetramethyl-2-(2-p-tolylvinyl)[1,3,2]dioxaborolane; With sodium periodate; In tetrahydrofuran; water; for 0.5h;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1002/cjoc.202000579

Reference yield:

bis(pinacol)diborane (73183-34-3) + 4-n-methylphenylacetylene (766-97-2) → 4-methylstyrenylboronic acid (214907-11-6)

Guidance literature:

bis(pinacol)diborane; With triphenylphosphine; copper(l) chloride; sodium t-butanolate; In tetrahydrofuran; at 20 ℃; for 0.166667h; Inert atmosphere; Schlenk technique;

4-n-methylphenylacetylene; In tetrahydrofuran; methanol; at 20 ℃; Inert atmosphere; Schlenk technique; Sealed tube;

With sodium periodate; ammonium acetate; In water; acetone; at 20 ℃; for 36h; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201700696

upstream raw materials:

bis(pinacol)diborane

4-n-methylphenylacetylene

benzo[1,3,2]dioxaborole

water

Downstream raw materials:

C₁₉H₂₄O₄

C₁₉H₂₄O₄

(S,E)-3-(hydroxymethyl)-1-phenyl-5-p-tolylpent-4-en-1-one

(E)-1-(2-iodovinyl)-4-methylbenzene