(4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

Base Information

Chemical Name:(4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone
CAS No.:1067221-97-9
Molecular Formula:C₁₅H₁₇NO₃
Molecular Weight:259.305
Hs Code.:

Synonyms:(4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

Suppliers and Price of (4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

There total 2 articles about (4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 80-59-1
Tiglic acid

: 40217-17-2,90719-32-7,120574-96-1,102029-44-7
(R)-4-(phenylmethyl)-2-oxazolidinone

: 1067221-97-9
(4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

Guidance literature:: Tiglic acid; With pivaloyl chloride; triethylamine; In tetrahydrofuran; at -15 ℃;

(R)-4-(phenylmethyl)-2-oxazolidinone; With lithium chloride; In tetrahydrofuran; at 20 ℃; Further stages.;
DOI:10.1016/j.bmcl.2007.04.067

Reference yield:

: C₁₀H₁₆O₃

: 40217-17-2,90719-32-7,120574-96-1,102029-44-7
(R)-4-(phenylmethyl)-2-oxazolidinone

: 1067221-97-9
(4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

Guidance literature:: With lithium chloride; In tetrahydrofuran; at -15 - 20 ℃; for 13h; Inert atmosphere;
DOI:10.1248/cpb.57.920

Reference yield: 99.0%

: 1067221-97-9
(4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

: 18162-48-6
tert-butyldimethylsilyl chloride

: C₂₁H₃₁NO₃Si

Guidance literature:: (4R)-3-[(2E)-2-methyl-1-oxo-1-buten-1-yl]-4-(phenylmethyl)-2-oxazolidinone; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1.5h; Inert atmosphere;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/anie.201606679