6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide

Base Information

Chemical Name:6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide
CAS No.:104616-13-9
Molecular Formula:C₄₁H₄₆BrN₃O₁₃
Molecular Weight:868.733
Hs Code.:

Synonyms:6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide

Suppliers and Price of 6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide

There total 12 articles about 6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.5%

: 6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinyl-β-D-glucopyranosyluronate)-D-glucopyranose

: 104616-13-9
6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide

Guidance literature:: With 2,4,6-trimethyl-pyridine; N-(bromomethylene)-N-methylmethanaminium bromide; In dichloromethane; at 0 ℃; for 0.3h;
DOI:10.1016/0008-6215(88)84116-8

Reference yield:

: 40608-06-8
levulinic anhydride

: 104616-13-9
6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide

Guidance literature:: Multi-step reaction with 7 steps

1: N,N-dimethylaminopyridine / pyridine; tetrahydrofuran / 6 h / 0 °C

2: acetic acid; H₂O / 4 h

3: chromium(VI) oxide / acetone; aq. H₂SO₄ / 24 h / 0 °C

4: CH₂Cl₂

5: trifluoroacetic acid / 16 h / Ambient temperature

6: piperidine / tetrahydrofuran / 16 h / Ambient temperature

7: oxalyl bromide / CHCl₃; dimethylformamide / 2.5 h / Ambient temperature

With piperidine; chromium(VI) oxide; Oxalyl bromide; trifluoroacetic acid; dmap; In tetrahydrofuran; pyridine; dichloromethane; chloroform; sulfuric acid; water; acetic acid; N,N-dimethyl-formamide; acetone;

Reference yield:

: 100-39-0
benzyl bromide

: 104616-13-9
6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(methyl 2,3-di-O-benzyl-4-O-levulinoyl-β-D-glucopyranosyluronato)-α-D-glucopyranosyl bromide

Guidance literature:: Multi-step reaction with 10 steps

1: 99 percent / 1.) NaH / dimethylformamide / 1.) 1h, 2.) 16 h

2: acetic acid; H₂O / 16 h / Ambient temperature

3: pyridine; tetrahydrofuran / 27 h

4: N,N-dimethylaminopyridine / pyridine; tetrahydrofuran / 6 h / 0 °C

5: acetic acid; H₂O / 4 h

6: chromium(VI) oxide / acetone; aq. H₂SO₄ / 24 h / 0 °C

7: CH₂Cl₂

8: trifluoroacetic acid / 16 h / Ambient temperature

9: piperidine / tetrahydrofuran / 16 h / Ambient temperature

10: oxalyl bromide / CHCl₃; dimethylformamide / 2.5 h / Ambient temperature

With piperidine; chromium(VI) oxide; Oxalyl bromide; sodium hydride; trifluoroacetic acid; dmap; In tetrahydrofuran; pyridine; dichloromethane; chloroform; sulfuric acid; water; acetic acid; N,N-dimethyl-formamide; acetone;