(2,5-dibromophenyl)methaneamine

Base Information

• Chemical Name: (2,5-dibromophenyl)methaneamine
• CAS No.: 1214331-41-5
• Molecular Formula: C₇H₇Br₂N
• Molecular Weight: 264.947
• Mol file: 1214331-41-5.mol

Synonyms:(2,5-dibromophenyl)methaneamine

Chemical Property of (2,5-dibromophenyl)methaneamine

Chemical Property:

• Boiling Point: 303.9±27.0 °C(Predicted)
• Density: 1.868±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

(2,5-Dibromophenyl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,5-dibromophenyl)methaneamine

There total 5 articles about (2,5-dibromophenyl)methaneamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

2-(2,5-dibromobenzyl)isoindoline-1,3-dione → (2,5-dibromophenyl)methaneamine (1214331-41-5)

Guidance literature:

With hydrazine; In ethanol; at 90 ℃; for 5h;

DOI:10.1002/pola.27621

Reference yield:

2,5-dibromobenzoic acid methyl ester (57381-43-8) → (2,5-dibromophenyl)methaneamine (1214331-41-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonia / methanol / 20 h / 20 °C / Inert atmosphere

2: borane-THF / tetrahydrofuran / 24 h / Reflux

With borane-THF; ammonia; In tetrahydrofuran; methanol;

DOI:10.1021/ja503296c

Reference yield:

2,5-dibromobenzamide (170492-50-9) → (2,5-dibromophenyl)methaneamine (1214331-41-5)

Guidance literature:

2,5-dibromobenzamide; With borane-THF; In tetrahydrofuran; for 24h; Reflux;

With hydrogenchloride; In tetrahydrofuran;

DOI:10.1021/ja503296c

upstream raw materials:

2,5-dibromobenzoic acid methyl ester

2,5-dibromobenzamide

1,4-dibromo-2-methylbenzene

1,4-dibromo-2-(bromomethyl)benzene

Downstream raw materials:

tert-butyl N-[(2,5-dibromophenyl)methyl]carbamate

Refernces

• 1、 -. "METAL ORGANIC FRAMEWORKS COMPRISING A PLURALITY OF SBUS WITH DIFFERENT METAL IONS AND/OR A PLURALITY OF ORGANIC LINKING LIGANDS WITH DIFFERENT FUNCTIONAL GROUPS.". . . Retrieved 2016/05/24.
• 2、 Fracaroli, Alejandro M.,Furukawa, Hiroyasu,Suzuki, Mitsuharu,Dodd, Matthew,Okajima, Satoshi,Gándara, Felipe,Reimer, Jeffrey A.,Yaghi, Omar M.. "Metal-organic frameworks with precisely designed interior for carbon dioxide capture in the presence of water". . p. 8863 - 8866. Retrieved 2014/07/08.