2,5-dibromobenzamide

Base Information

• Chemical Name: 2,5-dibromobenzamide
• CAS No.: 170492-50-9
• Molecular Formula: C₇H₅Br₂NO
• Molecular Weight: 278.931
• Mol file: 170492-50-9.mol

Synonyms:

Chemical Property of 2,5-dibromobenzamide

Chemical Property:

• Boiling Point: 305.6±32.0 °C(Predicted)
• PKA: 14.74±0.50(Predicted)
• Density: 1.985±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

2,5-Dibromobenzamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-dibromobenzamide

There total 1 articles about 2,5-dibromobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 2,4,7-tribromotropone (29798-82-1) + ammonia (7664-41-7) → 2,5-dibromobenzamide (170492-50-9) + 2,4-dibromo-benzoic acid amide (874522-46-0)

Guidance literature:

DOI:10.1021/ja01630a010

Reference yield: 72.0%

ethanol (64-17-5) + 2,5-dibromobenzamide (170492-50-9) → 2-ethoxy-5-bromobenzamide (54924-78-6) + 6-bromo-2-(5-bromo-2-ethoxyphenyl)quinazolin-4(3H)-one

Guidance literature:

With copper(l) iodide; caesium carbonate; at 120 ℃; for 0.166667h; under 9308.91 Torr; Microwave irradiation;

DOI:10.1002/ejoc.201800660

Reference yield:

2,5-dibromobenzamide (170492-50-9) → (2,5-dibromophenyl)methaneamine (1214331-41-5)

Guidance literature:

2,5-dibromobenzamide; With borane-THF; In tetrahydrofuran; for 24h; Reflux;

With hydrogenchloride; In tetrahydrofuran;

DOI:10.1021/ja503296c

upstream raw materials:

methanol

2,4,7-tribromotropone

ammonia

Downstream raw materials:

(2,5-dibromophenyl)methaneamine

tert-butyl N-[(2,5-dibromophenyl)methyl]carbamate

2-ethoxy-5-bromobenzamide