ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate

Base Information

Chemical Name:ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate
CAS No.:1400674-68-1
Molecular Formula:C₁₆H₂₄O₆
Molecular Weight:312.363
Hs Code.:

Synonyms:ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate

Suppliers and Price of ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate

There total 5 articles about ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.9%

: 2033-24-1
cycl-isopropylidene malonate

: 147905-77-9
ethyl 1-methyl-4-oxo-1-cyclohexanecarboxylate

: 1400674-68-1
ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate

Guidance literature:: With sodium tris(acetoxy)borohydride; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/acsmedchemlett.0c00200

Reference yield:

: 2033-24-1
cycl-isopropylidene malonate

: 147905-77-9
ethyl 1-methyl-4-oxo-1-cyclohexanecarboxylate

: 1400674-68-1
ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate

: 1354806-09-9
ethyl cis-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate

Guidance literature:: With sodium tris(acetoxy)borohydride; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

Reference yield:

: 17159-79-4
ethyl 4-oxocyclohexane-1-carboxylate

: 1400674-68-1
ethyl trans-4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-methylcyclohexanecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: toluene-4-sulfonic acid / toluene / 20 °C

2.1: lithium diisopropyl amide / tetrahydrofuran / 0.42 h / -30 °C

2.2: 1.08 h / -5 - 23 °C

3.1: hydrogenchloride / water; acetone / 20 °C

4.1: sodium tris(acetoxy)borohydride / N,N-dimethyl-formamide / 4 h / 20 °C

With hydrogenchloride; sodium tris(acetoxy)borohydride; toluene-4-sulfonic acid; lithium diisopropyl amide; In tetrahydrofuran; water; N,N-dimethyl-formamide; acetone; toluene;