tert-butyl 3-(4-dimethylaminobenzamido)-3-phenylpropanoate

Base Information

Chemical Name:tert-butyl 3-(4-dimethylaminobenzamido)-3-phenylpropanoate
CAS No.:861256-31-7
Molecular Formula:C₂₂H₂₈N₂O₃
Molecular Weight:368.476
Hs Code.:

Synonyms:tert-butyl 3-(4-dimethylaminobenzamido)-3-phenylpropanoate

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Chemical Property of tert-butyl 3-(4-dimethylaminobenzamido)-3-phenylpropanoate

Chemical Property:

Purity/Quality:

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MSDS Files:: SDS file from LookChem

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Technology Process of tert-butyl 3-(4-dimethylaminobenzamido)-3-phenylpropanoate

There total 3 articles about tert-butyl 3-(4-dimethylaminobenzamido)-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 861256-22-6
tert-butyl 3-(4-dimethylaminobenzamido)-2-diazo-3-phenylpropanoate

: 861256-31-7
tert-butyl 3-(4-dimethylaminobenzamido)-3-phenylpropanoate

Guidance literature:: With platinum(IV) oxide; hydrogen; In acetic acid; ethyl acetate; for 6h; under 760 Torr;
DOI:10.1021/ja051922a

Reference yield:

: N-benzylidene-4-(dimethylamino)benzamide

: 861256-31-7
tert-butyl 3-(4-dimethylaminobenzamido)-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / (R)-binaphthyl monpohosphoric acid derivative / toluene / 24 h / 20 °C

2: 79 percent / H₂; PtO₂ / ethyl acetate; acetic acid / 6 h / 760 Torr

With platinum(IV) oxide; (R)-binaphthyl monpohosphoric acid derivative; hydrogen; In acetic acid; ethyl acetate; toluene;
DOI:10.1021/ja051922a

Reference yield:

: N-(methoxyphenylmethyl)-4-(dimethylamino)benzamide

: 861256-31-7
tert-butyl 3-(4-dimethylaminobenzamido)-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: K₂CO₃; Na₂SO₄ / toluene / 12 h / Heating

1.2: 80 percent / Ac₂O / toluene / 0.5 h / 20 °C

2.1: 81 percent / (R)-binaphthyl monpohosphoric acid derivative / toluene / 24 h / 20 °C

3.1: 79 percent / H₂; PtO₂ / ethyl acetate; acetic acid / 6 h / 760 Torr

With platinum(IV) oxide; (R)-binaphthyl monpohosphoric acid derivative; hydrogen; potassium carbonate; sodium sulfate; In acetic acid; ethyl acetate; toluene;
DOI:10.1021/ja051922a