DB₁₈₅₅

Base Information

• Chemical Name: DB₁₈₅₅
• CAS No.: 1322586-87-7
• Molecular Formula: C₃₂H₃₂N₈O₃
• Molecular Weight: 576.658
• Mol file: 1322586-87-7.mol

Synonyms:DB₁₈₅₅

Chemical Property of DB₁₈₅₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of DB₁₈₅₅

There total 6 articles about DB₁₈₅₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H13N3S (1620724-26-6) + 2,5-bis[4-amino-2-(propan-2-yloxy)phenyl]furan → DB1855 (1322586-87-7)

Guidance literature:

In ethanol; acetonitrile; at 20 ℃; Cooling with ice;

DOI:10.1016/j.ejmech.2014.06.022

Reference yield:

2,5-bis[4-nitro-2-(propan-2-yloxy)phenyl]furan → DB1855 (1322586-87-7)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / ethyl acetate; ethanol / 3 h / 20 °C / 2585.81 Torr

2: ethanol; acetonitrile / 20 °C / Cooling with ice

With palladium 10% on activated carbon; hydrogen; In ethanol; ethyl acetate; acetonitrile;

DOI:10.1016/j.ejmech.2014.06.022

Reference yield:

2-bromo-5-nitrophenol (52427-05-1) → DB1855 (1322586-87-7)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium tert-butylate

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 80 - 90 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen / ethyl acetate; ethanol / 3 h / 20 °C / 2585.81 Torr

4: ethanol; acetonitrile / 20 °C / Cooling with ice

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; potassium tert-butylate; hydrogen; In 1,4-dioxane; ethanol; ethyl acetate; acetonitrile; 2: |Stille Cross-Coupling (Migita-Kosugi-Stille Coupling);

DOI:10.1016/j.ejmech.2014.06.022

upstream raw materials:

2-bromo-5-nitrophenol

5-Nitro-2-aminophenol

C₁₆H₁₃N₃S

pyrazine-2-carbothioamide