(2-CARBOXY-1-PHENYLETHYL)TRIPHENYLPHOSPHONIUM BROMIDE

Base Information

• Chemical Name: (2-CARBOXY-1-PHENYLETHYL)TRIPHENYLPHOSPHONIUM BROMIDE
• CAS No.: 29149-30-2
• Molecular Formula: C27H24 O2 P . Br
• Molecular Weight: 491.36
• Hs Code.: 2931900090
• Mol file: 29149-30-2.mol

Synonyms:Phosphonium,(2-carboxy-1-phenylethyl)triphenyl-, bromide (9CI); Phosphonium, [a-(carboxymethyl)benzyl]triphenyl-,bromide (8CI); [a-(Carboxymethyl)benzyl]triphenylphosphonium bromide (6CI)

Chemical Property of (2-CARBOXY-1-PHENYLETHYL)TRIPHENYLPHOSPHONIUM BROMIDE

Chemical Property:

• PSA: 50.89000
• LogP: 2.20050

Purity/Quality:

99%min ^*data from raw suppliers

P (2-CARBOXY-1-PHENYLETHYL)TRIPHENYLPHOSPHONIUM BROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-CARBOXY-1-PHENYLETHYL)TRIPHENYLPHOSPHONIUM BROMIDE

There total 1 articles about (2-CARBOXY-1-PHENYLETHYL)TRIPHENYLPHOSPHONIUM BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (2-Carboxy-1-phenyl-ethyl)-triphenyl-phosphonium; bromide (29149-30-2)

Guidance literature:

Ph3P, Saeure 7B;

DOI:10.1039/j39700001901

Reference yield:

(2-Carboxy-1-phenyl-ethyl)-triphenyl-phosphonium; bromide (29149-30-2) + benzaldehyde (100-52-7) → 3,4c-diphenyl-but-3-enoic acid (42842-82-0)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; for 12h;

DOI:10.1055/s-0040-1707111

Reference yield:

(2-Carboxy-1-phenyl-ethyl)-triphenyl-phosphonium; bromide (29149-30-2) + benzaldehyde (100-52-7) → 3,4c-diphenyl-but-3-enoic acid methyl ester (42842-88-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 12 h

2: caesium carbonate / acetone / 3 h / 80 °C

With potassium tert-butylate; caesium carbonate; In tetrahydrofuran; acetone;

DOI:10.1055/s-0040-1707111

Downstream raw materials:

3,4c-diphenyl-but-3-enoic acid

3,4c-diphenyl-but-3-enoic acid methyl ester