2-(3-Bromopropyl)-5-nitroisoindoline-1,3-dione

Base Information

• Chemical Name: 2-(3-Bromopropyl)-5-nitroisoindoline-1,3-dione
• CAS No.: 140715-56-6
• Molecular Formula: C₁₁H₉BrN₂O₄
• Molecular Weight: 313.107
• Hs Code.: 2925190090
• DSSTox Substance ID: DTXSID20370838
• Wikidata: Q82157993
• Mol file: 140715-56-6.mol

Synonyms:140715-56-6;2-(3-bromopropyl)-5-nitroisoindoline-1,3-dione;2-(3-bromopropyl)-5-nitroisoindole-1,3-dione;1H-Isoindole-1,3(2H)-dione,2-(3-bromopropyl)-5-nitro-;2-(3-Bromopropyl)-5-nitro-1H-isoindole-1,3(2H)-dione;DTXSID20370838;MFCD00833387;AKOS009157842;N-(3-Bromoprop-1-yl)-4-nitrophthalimide;FT-0608540;A807686;2-(3-bromanylpropyl)-5-nitro-isoindole-1,3-dione;2-(3-bromopropyl)-5-nitro-2,3-dihydro-1H-isoindole-1,3-dione

Chemical Property of 2-(3-Bromopropyl)-5-nitroisoindoline-1,3-dione

Chemical Property:

• Vapor Pressure: 4.76E-08mmHg at 25°C
• Melting Point: 104-107
• Boiling Point: 443.1°Cat760mmHg
• Flash Point: 221.8°C
• PSA: 83.20000
• Density: 1.723g/cm³
• LogP: 2.43690
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 311.97457
• Heavy Atom Count: 18
• Complexity: 382

Purity/Quality:

97% ^*data from raw suppliers

N-(3-Bromoprop-1-yl)-4-nitrophthalimide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1[N+](=O)[O-])C(=O)N(C2=O)CCCBr

Technology Process of 2-(3-Bromopropyl)-5-nitroisoindoline-1,3-dione

There total 3 articles about 2-(3-Bromopropyl)-5-nitroisoindoline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitrophthalimide (89-40-7) → 2-(3-Bromo-propyl)-5-nitro-isoindole-1,3-dione (140715-56-6)

Guidance literature:

4-nitrophthalimide; With potassium hydroxide; In methanol; ethanol; at 20 ℃; for 3h;

3-bromopropyl halide; With potassium carbonate; In N,N-dimethyl-formamide; for 1h; Reflux;

DOI:10.1016/j.bmcl.2013.02.011

Reference yield:

phthalimide (136918-14-4,85-41-6) → 2-(3-Bromo-propyl)-5-nitro-isoindole-1,3-dione (140715-56-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: nitric acid; sulfuric acid / 16 h / 5 - 20 °C

2.1: potassium hydroxide / methanol; ethanol / 3 h / 20 °C

2.2: 1 h / Reflux

With sulfuric acid; nitric acid; potassium hydroxide; In methanol; ethanol;

DOI:10.1016/j.bmcl.2013.02.011

Reference yield:

4-nitrophthalimide (89-40-7) + 1,3-dibromo-propane (109-64-8) → 2-(3-Bromo-propyl)-5-nitro-isoindole-1,3-dione (140715-56-6)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 60 deg C, 30 min, 2.) DMF, acetone, reflux, 16 h;

DOI:10.1248/cpb.39.3225

upstream raw materials:

4-nitrophthalimide

1,3-dibromo-propane

phthalimide

Downstream raw materials:

C₁₈H₁₇BrN₂O₄S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

✦Write with AI

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 140715-56-6 2-(3-BROMOPROPYL)-5-NITROISOINDOLINE-1,3-DIONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send