tert-butyl 2-{[(4-methoxybenzyl)(trichloroacetyl)amino]methyl}-1H-indole-1-carboxylate

Base Information

Chemical Name:tert-butyl 2-{[(4-methoxybenzyl)(trichloroacetyl)amino]methyl}-1H-indole-1-carboxylate
CAS No.:1258221-43-0
Molecular Formula:C₂₄H₂₅Cl₃N₂O₄
Molecular Weight:511.832
Hs Code.:

Synonyms:tert-butyl 2-{[(4-methoxybenzyl)(trichloroacetyl)amino]methyl}-1H-indole-1-carboxylate

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Chemical Property of tert-butyl 2-{[(4-methoxybenzyl)(trichloroacetyl)amino]methyl}-1H-indole-1-carboxylate

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Technology Process of tert-butyl 2-{[(4-methoxybenzyl)(trichloroacetyl)amino]methyl}-1H-indole-1-carboxylate

There total 1 articles about tert-butyl 2-{[(4-methoxybenzyl)(trichloroacetyl)amino]methyl}-1H-indole-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 1258221-37-2
tert-butyl 2-[(4-methoxybenzylamino)methyl]-1H-indole-1-carboxylate

: 76-02-8
trifluoroacetyl chloride

: 1258221-43-0
tert-butyl 2-{[(4-methoxybenzyl)(trichloroacetyl)amino]methyl}-1H-indole-1-carboxylate

Guidance literature:: With pyridine; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere; Darkness;
DOI:10.1002/ejoc.201000757

Reference yield: 20.0%

: 1258221-43-0
tert-butyl 2-{[(4-methoxybenzyl)(trichloroacetyl)amino]methyl}-1H-indole-1-carboxylate

: 1258221-48-5
C₂₄H₂₅Cl₃N₂O₄

Guidance literature:: With N,N,N',N'',N'''-pentamethyldiethylenetriamine; copper(l) chloride; In dichloromethane; for 24h; Inert atmosphere; Reflux;
DOI:10.1002/ejoc.201000757