tert-butyl (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenylthio)-quinolin-3-yl]-3,5-O-isoproylidene-6-heptenoate

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Chemical Name:tert-butyl (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenylthio)-quinolin-3-yl]-3,5-O-isoproylidene-6-heptenoate
CAS No.:1202383-17-2
Molecular Formula:C₃₂H₃₆FNO₄S
Molecular Weight:549.707
Hs Code.:

Synonyms:tert-butyl (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenylthio)-quinolin-3-yl]-3,5-O-isoproylidene-6-heptenoate

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Chemical Property of tert-butyl (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenylthio)-quinolin-3-yl]-3,5-O-isoproylidene-6-heptenoate

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Technology Process of tert-butyl (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenylthio)-quinolin-3-yl]-3,5-O-isoproylidene-6-heptenoate

There total 1 articles about tert-butyl (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenylthio)-quinolin-3-yl]-3,5-O-isoproylidene-6-heptenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1202383-35-4
2-cyclopropyl-4-(4-fluorohenylthio)-3-((diphenyl-oxo-phosphonyl)methyl)-quinoline

: 124752-23-4
tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate

: 1202383-17-2
tert-butyl (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenylthio)-quinolin-3-yl]-3,5-O-isoproylidene-6-heptenoate

Guidance literature:: 2-cyclopropyl-4-(4-fluorohenylthio)-3-((diphenyl-oxo-phosphonyl)methyl)-quinoline; With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2009.10.021