1-(3-Fluorobenzyl)-4-(hydroxymethyl)-1H-1,2,3-triazole

Base Information

Chemical Name:1-(3-Fluorobenzyl)-4-(hydroxymethyl)-1H-1,2,3-triazole
CAS No.:952183-23-2
Molecular Formula:C₁₀H₁₀FN₃O
Molecular Weight:207.207
Hs Code.:2933998090
Mol file:952183-23-2.mol

Synonyms:1-[(3-fluorophenyl)methyl]-4-hydroxymethyl-1H-1,2,3-triazole

Suppliers and Price of 1-(3-Fluorobenzyl)-4-(hydroxymethyl)-1H-1,2,3-triazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1-(3-Fluorobenzyl)-4-(hydroxymethyl)-1H-1,2,3-triazole
1 g
$ 192.00

Matrix Scientific
[1-(3-Fluorobenzyl)-1H-1,2,3-triazol-4-yl]methanol >95%
1g
$ 304.00

Matrix Scientific
[1-(3-Fluorobenzyl)-1H-1,2,3-triazol-4-yl]methanol >95%
500mg
$ 244.00

Apolloscientific
1-(3-Fluorobenzyl)-4-(hydroxymethyl)-1H-1,2,3-triazole
1g
$ 120.00

American Custom Chemicals Corporation
1-(3-FLUOROBENZYL)-4-(HYDROXYMETHYL)-1H-1,2,3-TRIAZOLE 95.00%
1G
$ 752.14

Total 3 raw suppliers

Chemical Property of 1-(3-Fluorobenzyl)-4-(hydroxymethyl)-1H-1,2,3-triazole

Chemical Property:

Melting Point:64-66

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Fluorobenzyl)-4-(hydroxymethyl)-1H-1,2,3-triazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:

Useful:

Technology Process of 1-(3-Fluorobenzyl)-4-(hydroxymethyl)-1H-1,2,3-triazole

There total 3 articles about 1-(3-Fluorobenzyl)-4-(hydroxymethyl)-1H-1,2,3-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 107-19-7
propargyl alcohol

: 456-41-7
1-(Bromomethyl)-3-fluorobenzene

: 952183-23-2
1-[(3-fluorophenyl)methyl]-4-hydroxymethyl-1H-1,2,3-triazole

Guidance literature:: With sodium azide; copper(ll) sulfate pentahydrate; sodium carbonate; sodium L-ascorbate; L-proline; In water; dimethyl sulfoxide; at 65 ℃; for 18h; Inert atmosphere; Schlenk technique;
DOI:10.1016/j.tet.2013.07.070

Reference yield:

: 159979-97-2
3-fluorobenzylazide

: 107-19-7
propargyl alcohol

: 952183-23-2
1-[(3-fluorophenyl)methyl]-4-hydroxymethyl-1H-1,2,3-triazole

Guidance literature:: With copper diacetate; In water; tert-butyl alcohol; at 20 ℃; for 16h;
DOI:10.1002/cmdc.202100676

Reference yield:

: 456-41-7
1-(Bromomethyl)-3-fluorobenzene

: 952183-23-2
1-[(3-fluorophenyl)methyl]-4-hydroxymethyl-1H-1,2,3-triazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / acetonitrile; N,N-dimethyl-formamide / 16 h / 100 °C

2: copper diacetate / water; tert-butyl alcohol / 16 h / 20 °C

With sodium azide; copper diacetate; In water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;
DOI:10.1002/cmdc.202100676