Technology Process of (5R,8R)-1-(benzoyloxy)-5,8-dodecanediol
There total 6 articles about (5R,8R)-1-(benzoyloxy)-5,8-dodecanediol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
for 2h;
Ambient temperature;
DOI:10.1021/jo00045a034
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 46 percent / 4-(dimethylamino)pyridine / CH2Cl2 / 1.5 h / Ambient temperature
2: 92 percent / CBr4, triphenylphosphine / CH2Cl2 / 0.17 h / 0 °C
3: 84 percent / triethylamine, H2 / 10percent Pd-C / methanol / 1 h / 760 Torr
4: 91 percent / 1 M tetrabutylammonium fluoride / tetrahydrofuran / 2 h / Ambient temperature
With
dmap; carbon tetrabromide; tetrabutyl ammonium fluoride; hydrogen; triethylamine; triphenylphosphine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo00045a034
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 46 percent / 4-(dimethylamino)pyridine / CH2Cl2 / 1.5 h / Ambient temperature
2: 92 percent / CBr4, triphenylphosphine / CH2Cl2 / 0.17 h / 0 °C
3: 84 percent / triethylamine, H2 / 10percent Pd-C / methanol / 1 h / 760 Torr
4: 91 percent / 1 M tetrabutylammonium fluoride / tetrahydrofuran / 2 h / Ambient temperature
With
dmap; carbon tetrabromide; tetrabutyl ammonium fluoride; hydrogen; triethylamine; triphenylphosphine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo00045a034
