ethyl 5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanimidate hydrochloride

Base Information

• Chemical Name: ethyl 5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanimidate hydrochloride
• CAS No.: 1240469-37-7
• Molecular Formula: C₁₄H₁₆ClF₄NO*ClH
• Molecular Weight: 362.195

Synonyms:ethyl 5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanimidate hydrochloride

Chemical Property of ethyl 5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanimidate hydrochloride

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Technology Process of ethyl 5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanimidate hydrochloride

There total 1 articles about ethyl 5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanimidate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + 5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanenitrile (1240469-64-0) → ethyl 5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanimidate hydrochloride (1240469-37-7)

Guidance literature:

With hydrogenchloride; at 20 ℃; Cooling with ice;

Reference yield:

(E)-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyrazin-2-yl]acrylic acid hydrazide trihydrochloride + ethyl 5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanimidate hydrochloride (1240469-37-7) → (+)-8-(4-fluoro-2-trifluoromethylphenyl)-2-{(E)-2-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyrazin-2-yl]vinyl}-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridine + (-)-8-(4-fluoro-2-trifluoromethylphenyl)-2-{(E)-2-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyrazin-2-yl]vinyl}-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridine

Guidance literature:

With 1H-imidazole; In methanol; at 20 - 50 ℃;

upstream raw materials:

ethanol

5-chloro-2-(4-fluoro-2-trifluoromethylphenyl)pentanenitrile

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