4-(Trimethylsilyl)-3-butyn-2-one

Base Information

Chemical Name:4-(Trimethylsilyl)-3-butyn-2-one
CAS No.:5930-98-3
Molecular Formula:C7H12OSi
Molecular Weight:140.257
Hs Code.:29319090
European Community (EC) Number:628-294-1
DSSTox Substance ID:DTXSID20370434
Nikkaji Number:J911.706G
Wikidata:Q72514438
Mol file:5930-98-3.mol

Synonyms:4-(trimethylsilyl)-3-butyn-2-one;TMSB compound

Suppliers and Price of 4-(Trimethylsilyl)-3-butyn-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Trimethylsilyl)-3-butyn-2-one
10mg
$ 45.00

TCI Chemical
4-(Trimethylsilyl)-3-butyn-2-one >97.0%(GC)
25mL
$ 290.00

TCI Chemical
4-(Trimethylsilyl)-3-butyn-2-one >97.0%(GC)
5mL
$ 85.00

Sigma-Aldrich
4-(Trimethylsilyl)-3-butyn-2-one 97%
5g
$ 111.00

Matrix Scientific
4-(Trimethylsilyl)-3-butyn-2-one 95+%
1g
$ 24.00

Matrix Scientific
4-(Trimethylsilyl)-3-butyn-2-one 95+%
5g
$ 93.00

Matrix Scientific
4-(Trimethylsilyl)-3-butyn-2-one 95+%
10g
$ 155.00

GFS CHEMICALS
4-TMS-3-BUTYN-2-ONE
10 G
$ 166.22

Chem-Impex
4-(Trimethylsilyl)-3-butyn-2-one,97%(GC) 97%(GC)
5ML
$ 84.00

Chem-Impex
4-(Trimethylsilyl)-3-butyn-2-one,≥97%(GC)Hazmat ≥97%(GC)
25ML
$ 321.48

Total 85 raw suppliers

Chemical Property of 4-(Trimethylsilyl)-3-butyn-2-one

Chemical Property:

Appearance/Colour:clear slightly yellow liquid
Vapor Pressure:2.03E-05mmHg at 25°C
Melting Point:99 °C
Refractive Index:n20/D 1.442(lit.)
Boiling Point:144.6 °C at 760 mmHg
Flash Point:41.2 °C
PSA：17.07000
Density:0.875 g/cm³
LogP:1.45620
Storage Temp.:Flammables area
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:140.065741536
Heavy Atom Count:9
Complexity:174

Purity/Quality:

99% ^*data from raw suppliers

4-(Trimethylsilyl)-3-butyn-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 10-36/37/38
Safety Statements: 16-26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C#C[Si](C)(C)C
Uses 4-(Trimethylsilyl)-3-butyn-2-one (TMSB) has been used to investigate its asymmetric bioreduction to (S)-4-(trimethylsilyl)-3-butyn-2-ol {(S)-TMSBOL} by employing biocompatible water-immiscible ionic liquids (ILs). TMSB may be used for the synthesis of entecavir (BMS-200475).

Technology Process of 4-(Trimethylsilyl)-3-butyn-2-one

There total 19 articles about 4-(Trimethylsilyl)-3-butyn-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: (η5-C5H4Si(CH3)3)2Ti(CCC(CH3)3)2CuCCSi(CH3)3

: 108-24-7
acetic anhydride

: (C₅H₄Si(CH₃)3)2Ti(C₂C(CH₃)3)2CuOCOCH₃

: 5930-98-3
4-trimethylsilyl-3-butyn-2-one

Guidance literature:: In tetrahydrofuran; acetic anhydride was added dropwise to a soln. of complex in THF at -20°C, stirred for 1 h, gradually warmed to 25°C, stirred for 2 h at 25°C; volatiles were removed in vac., the organic products were extd. with cold (-20°C) diethyl ether, the residue was dried in vac.;
DOI:10.1016/S0022-328X(00)00793-2

Reference yield: 92.33%

: 75-36-5
acetyl chloride

: 14630-40-1
Bis(trimethylsilyl)ethyne

: 5930-98-3
4-trimethylsilyl-3-butyn-2-one

Guidance literature:: With aluminium trichloride; In carbon disulfide;

Reference yield: 90.0%

: 103253-60-7,121522-26-7,121522-27-8,6999-19-5
4-trimethylsilyl-3-butyn-2-ol

: 5930-98-3
4-trimethylsilyl-3-butyn-2-one

Guidance literature:: With Iron(III) nitrate nonahydrate; 2,2,6,6-tetramethyl-piperidine-N-oxyl; oxygen; sodium chloride; In toluene; at 20 - 55 ℃; for 7.4h;
DOI:10.1055/s-0031-1290811