(2S,3S,6R)-3,5-Dimethyl-6-((S)-1-methyl-allyl)-2-phenyl-3,6-dihydro-2H-pyran

Base Information

• Chemical Name: (2S,3S,6R)-3,5-Dimethyl-6-((S)-1-methyl-allyl)-2-phenyl-3,6-dihydro-2H-pyran
• CAS No.: 106930-35-2
• Molecular Formula: C₁₇H₂₂O
• Molecular Weight: 242.361
• Mol file: 106930-35-2.mol

Synonyms:(2S,3S,6R)-3,5-Dimethyl-6-((S)-1-methyl-allyl)-2-phenyl-3,6-dihydro-2H-pyran

Chemical Property of (2S,3S,6R)-3,5-Dimethyl-6-((S)-1-methyl-allyl)-2-phenyl-3,6-dihydro-2H-pyran

Chemical Property:

Purity/Quality:

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Technology Process of (2S,3S,6R)-3,5-Dimethyl-6-((S)-1-methyl-allyl)-2-phenyl-3,6-dihydro-2H-pyran

There total 1 articles about (2S,3S,6R)-3,5-Dimethyl-6-((S)-1-methyl-allyl)-2-phenyl-3,6-dihydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3S,4S)-3,5-Dimethyl-2-phenyl-3,4-dihydro-2H-pyran-4-ol (106930-33-0) → (2S,3S,6R)-3,5-Dimethyl-6-((S)-1-methyl-allyl)-2-phenyl-3,6-dihydro-2H-pyran (106930-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridin, DMAP

2: BF₃*Et₂O / acetonitrile

With pyridine; dmap; boron trifluoride diethyl etherate; In acetonitrile;

DOI:10.1021/ja00241a028

Reference yield:

Phenylselenyl chloride (5707-04-0) + (2S,3S,6R)-3,5-Dimethyl-6-((S)-1-methyl-allyl)-2-phenyl-3,6-dihydro-2H-pyran (106930-35-2) → (3R,3aS,5R,6S,7R,7aR)-3,6,7a-Trimethyl-5-phenyl-7-phenylselanyl-hexahydro-furo[3,2-b]pyran (106930-44-3,106974-44-1)

Guidance literature:

With sodium tetrahydroborate; sodium periodate; Multistep reaction; 1.) EtOH, 2.) EtOH, 0 deg C;

DOI:10.1021/ja00241a028

upstream raw materials:

(2S,3S,4S)-3,5-Dimethyl-2-phenyl-3,4-dihydro-2H-pyran-4-ol

Downstream raw materials:

(3R,3aS,5R,6S,7R,7aR)-3,6,7a-Trimethyl-5-phenyl-7-phenylselanyl-hexahydro-furo[3,2-b]pyran