5-Iodo-2-phenoxypyridine

Base Information

Chemical Name:5-Iodo-2-phenoxypyridine
CAS No.:352018-92-9
Molecular Formula:C11H8INO
Molecular Weight:297.095
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80380135
Wikidata:Q82170211
Mol file:352018-92-9.mol

Synonyms:5-iodo-2-phenoxypyridine;352018-92-9;5-Iodo-2-phenoxy-pyridine;SCHEMBL1697610;DTXSID80380135;CPA01892;MFCD02681952;AKOS015899832;PS-7150;A6183;CS-0316100;FT-0620510;J-517637

Suppliers and Price of 5-Iodo-2-phenoxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
5-Iodo-2-phenoxypyridine
5g
$ 738.72

Chemenu
5-Iodo-2-phenoxypyridine 95%
5g
$ 640.00

TRC
5-Iodo-2-phenoxypyridine
1g
$ 130.00

Total 18 raw suppliers

Chemical Property of 5-Iodo-2-phenoxypyridine

Chemical Property:

Vapor Pressure:0.000177mmHg at 25°C
Refractive Index:1.646
Boiling Point:339.8 °C at 760 mmHg
Flash Point:159.3 °C
PSA：22.12000
Density:1.694 g/cm³
LogP:3.47850
Storage Temp.:2-8°C
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:296.96506
Heavy Atom Count:14
Complexity:171

Purity/Quality:

97% ^*data from raw suppliers

5-Iodo-2-phenoxypyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.;
Hazard Codes: Xn:Harmful;
Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.;
Safety Statements: S36/37:Wear suitable protective clothing and gloves.;

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)OC2=NC=C(C=C2)I

Technology Process of 5-Iodo-2-phenoxypyridine

There total 5 articles about 5-Iodo-2-phenoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 25194-67-6
6-phenoxy-pyridin-3-ylamine

: 352018-92-9
5-iodo-2-phenoxypyridine

Guidance literature:: 6-phenoxy-pyridin-3-ylamine; With sulfuric acid; sodium nitrite; In water; at 5 ℃; for 1h;

With potassium iodide; In water; at 5 - 20 ℃;
DOI:10.1016/S0022-328X(03)00347-4

Reference yield:

: 73290-22-9
2-bromo-5-iodo-pyridine

: 108-95-2,27073-41-2
phenol

: 352018-92-9
5-iodo-2-phenoxypyridine

Guidance literature:: With 2-[(dimethylamino)methyl]-1-thiophenolato-copper(I); caesium carbonate; In dimethyl sulfoxide; at 160 ℃; for 16h; chemoselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2010.09.019

Reference yield:

: 4487-59-6
2-bromo-5-nitropyridine

: 352018-92-9
5-iodo-2-phenoxypyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: 93 percent / K₂CO₃ / dimethylsulfoxide / 4 h / 120 °C

2.1: 69 percent / tin; HCl; water / 2 h / 50 °C

3.1: H₂SO₄; NaNO₂ / H₂O / 1 h / 5 °C

3.2: 60 percent / potassium iodide / H₂O / 5 - 20 °C

With hydrogenchloride; tin; sulfuric acid; water; potassium carbonate; sodium nitrite; In water; dimethyl sulfoxide;
DOI:10.1016/S0022-328X(03)00347-4