C₃₇H₃₃N₂O₂⁽¹⁺⁾*Cl^(1-)

Base Information

• Chemical Name: C₃₇H₃₃N₂O₂⁽¹⁺⁾*Cl^(1-)
• CAS No.: 1414888-92-8
• Molecular Formula: C₃₇H₃₃N₂O₂*Cl
• Molecular Weight: 573.134
• Mol file: 1414888-92-8.mol

Synonyms:C₃₇H₃₃N₂O₂⁽¹⁺⁾*Cl^(1-)

Chemical Property of C₃₇H₃₃N₂O₂⁽¹⁺⁾*Cl^(1-)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₃₃N₂O₂⁽¹⁺⁾*Cl^(1-)

There total 4 articles about C₃₇H₃₃N₂O₂⁽¹⁺⁾*Cl^(1-) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

C36H34N2O2 (1414888-91-7) + orthoformic acid triethyl ester (122-51-0) → C37H33N2O2(1+)*Cl(1-) (1414888-92-8)

Guidance literature:

C₃₆H₃₄N₂O₂; With hydrogenchloride; In 1,4-dioxane; dichloromethane; for 2h; Inert atmosphere;

orthoformic acid triethyl ester; at 125 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.09.116 DOI:10.1016/j.tetlet.2012.09.116

Reference yield:

{4-[3-(4-hydroxymethyl-phenoxymethyl)-benzyloxy]-phenyl}-methanol (565462-34-2) → C37H33N2O2(1+)*Cl(1-) (1414888-92-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: phosphorus tribromide / dichloromethane / 20 °C / Inert atmosphere

2.1: potassium carbonate; tetraethylammonium bromide / acetonitrile / 48 h / Reflux; Inert atmosphere

3.1: hydrogenchloride / dichloromethane; 1,4-dioxane / 2 h / Inert atmosphere

3.2: 24 h / 125 °C / Inert atmosphere

With hydrogenchloride; tetraethylammonium bromide; phosphorus tribromide; potassium carbonate; In 1,4-dioxane; dichloromethane; acetonitrile;

DOI:10.1016/j.tetlet.2012.09.116 DOI:10.1016/j.tetlet.2012.09.116

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → C37H33N2O2(1+)*Cl(1-) (1414888-92-8)

Guidance literature:

Multi-step reaction with 5 steps

1.1: potassium carbonate / acetonitrile / Reflux; Inert atmosphere

2.1: sodium tetrahydroborate / methanol / 20 °C / Inert atmosphere

3.1: phosphorus tribromide / dichloromethane / 20 °C / Inert atmosphere

4.1: potassium carbonate; tetraethylammonium bromide / acetonitrile / 48 h / Reflux; Inert atmosphere

5.1: hydrogenchloride / dichloromethane; 1,4-dioxane / 2 h / Inert atmosphere

5.2: 24 h / 125 °C / Inert atmosphere

With hydrogenchloride; sodium tetrahydroborate; tetraethylammonium bromide; phosphorus tribromide; potassium carbonate; In 1,4-dioxane; methanol; dichloromethane; acetonitrile;

DOI:10.1016/j.tetlet.2012.09.116 DOI:10.1016/j.tetlet.2012.09.116

upstream raw materials:

4-hydroxy-benzaldehyde

4,4′-[1,3-phenylenebis(methyleneoxy)]bisbenzaldehyde

{4-[3-(4-hydroxymethyl-phenoxymethyl)-benzyloxy]-phenyl}-methanol

C₃₆H₃₄N₂O₂

Downstream raw materials:

C₃₇H₃₂N₂O₂S