4-Chloropyridazin-3-ol

Base Information

• Chemical Name: 4-Chloropyridazin-3-ol
• CAS No.: 1677-79-8
• Molecular Formula: C4H3 Cl N2 O
• Molecular Weight: 130.534
• Hs Code.: 2933990090
• European Community (EC) Number: 890-397-4
• DSSTox Substance ID: DTXSID90592020
• Nikkaji Number: J2.392.381E
• Wikidata: Q82485911
• Mol file: 1677-79-8.mol

Synonyms:4-Chloropyridazin-3-ol;1677-79-8;4-CHLOROPYRIDAZIN-3(2H)-ONE;4-CHLORO-3(2H)-PYRIDAZINONE;5-chloro-1H-pyridazin-6-one;3(2H)-Pyridazinone, 4-chloro-;4-CHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE;4-chloro-2h-pyridazin-3-one;4-CHLORO-3-PYRIDAZONE;Chlorpyridazon;SCHEMBL392004;SCHEMBL8824541;DTXSID90592020;UYWAYTBDMJFIQT-UHFFFAOYSA-N;AMY25003;MFCD00233956;MFCD08062119;AKOS006284219;AKOS015998721;CS-W019136;GS-3821;PB31005;AC-27258;SY033523;DB-358284;EN300-85858;A882216;4-Chloro-3(2H)-Pyridazinone

Chemical Property of 4-Chloropyridazin-3-ol

Chemical Property:

• PKA: 9.80±0.40(Predicted)
• PSA: 45.75000
• Density: 1.55±0.1 g/cm3(Predicted)
• LogP: 0.42330
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 129.9933904
• Heavy Atom Count: 8
• Complexity: 173

Purity/Quality:

97% ^*data from raw suppliers

4-Chloropyridazin-3-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=O)NN=C1)Cl

Technology Process of 4-Chloropyridazin-3-ol

There total 5 articles about 4-Chloropyridazin-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.5%

C4H4Cl2N4 → 4-chloropyridazin-3-ol (1677-79-8)

Guidance literature:

With manganese(IV) oxide; In tetrahydrofuran; at 25 ℃; for 8h; Temperature;

Reference yield:

4-Chloro-5-hydrazino-3(2H)-pyridazinone (6959-56-4) → 4-chloro-2,3-dihydropyridazin-3-one (1677-79-8)

Guidance literature:

4-Chloro-5-hydrazino-3(2H)-pyridazinone; With copper(ll) sulfate pentahydrate; In water; under 760.051 Torr; Inert atmosphere; Reflux;

With sodium hydroxide; In water; at 0 ℃; pH=4;

Reference yield:

4-chloro-5-hydrazinyl-3(2H)-pyridazinone (1314898-43-5) → 4-chloro-2,3-dihydropyridazin-3-one (1677-79-8)

Guidance literature:

4-chloro-5-hydrazinyl-3(2H)-pyridazinone; With CuH₁₀O₉S; In water; Reflux;

With sodium hydroxide; In water; at 0 ℃; pH=4;

upstream raw materials:

4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-2H-pyridazin-3-one

4-Chloro-5-hydrazino-3(2H)-pyridazinone

4-chloro-5-hydrazinyl-3(2H)-pyridazinone

Downstream raw materials:

3,4-dicholoropyridazine

4-chloro-2-methyl-pyridazine-3(2H)-one

4-phenyl-2,3-dihydropyridazin-3-one