1,5,9-Triazacyclododecane

Base Information

• Chemical Name: 1,5,9-Triazacyclododecane
• CAS No.: 294-80-4
• Molecular Formula: C9H21N3
• Molecular Weight: 171.286
• Hs Code.: 2933990090
• Mol file: 294-80-4.mol

Synonyms:1,5,9-Triaza-cyclododecane;

Chemical Property of 1,5,9-Triazacyclododecane

Chemical Property:

• Vapor Pressure: 0.0847mmHg at 25°C
• Melting Point: 32-35 °C
• Refractive Index: 1.426
• Boiling Point: 225.8 °C at 760 mmHg
• Flash Point: 124.9 °C
• PSA: 36.09000
• Density: 0.852 g/cm³
• LogP: 0.92550

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,5,9-Triazacyclododecane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,5,9-Triazacyclododecane

There total 19 articles about 1,5,9-Triazacyclododecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,5,9-triazacyclododecane-2,4-dione (127623-71-6) → 1,5,9-triazacyclododecane (294-80-4)

Guidance literature:

With borane-THF; In tetrahydrofuran; for 24h; Heating;

DOI:10.1016/S0040-4039(02)02322-5

Reference yield: 94.0%

1,5,9-triazatricyclo[7.3.1.05,13 ]tridecane (67705-41-3) → 1,5,9-triazacyclododecane (294-80-4)

Guidance literature:

With sulfuric acid; for 9.5h; Heating;

DOI:10.1080/00397919408011324

Reference yield: 81.0%

N,N',N''-tris(β-trimethylsilylethanesulfonyl)-1,5,9-triazacyclododecane (340970-56-1) → 1,5,9-triazacyclododecane (294-80-4)

Guidance literature:

With cesium fluoride; In N,N-dimethyl-formamide; at 95 ℃; for 24h;

DOI:10.1021/jo001639o

upstream raw materials:

1,5,9-triazacyclododecane trihydrobromide

1,5,9-triazatricyclo[7.3.1.05,13 ]tridecane

1,5,9-tritosyl-1,5,9-triazacyclododecane

N,N',N''-tris(β-trimethylsilylethanesulfonyl)-1,5,9-triazacyclododecane

Downstream raw materials:

hexahydro-3a,6a,9a-triaza-9b-phospha-phenalene

succinic acid

triethylamine hydrobromide

1,5,9-tris[3-((Z)-4,4,4-trifluoro-3-hydroxybut-2-en-1-onyl)phenylmethyl]-1,5,9-triazacyclododecane

Refernces

• 1、 Choi, Heung-Jin,Bae, Yoon-Kyung,Kang, Seok-Chan,Sil Park, Yeon,Won Park, Joon,Kim, Woong-Il,Bell, Thomas W. "Strongly basic macrocyclic triamines, 1,5,9-triazacyclododecanes for solvent extraction of gold(I) cyanide". . p. 9385 - 9389. Retrieved 2002.
• 2、 Panetta-Le Mer, V.,Yaouanc, J. J.,Handel, H.. "Synthesis of 24-, 26-, 32- and 36-membered Macrocyclic Polyamines via a (2+2) Cyclization Process". . p. 2337 - 2340. Retrieved 1994.
• 3、 Alexandrova, Anastasia V.,Masek, Tomas,Polyakova, Svetlana M.,Cisarova, Ivana,Saame, Jaan,Leito, Ivo,Lyapkalo, Ilya M.. "Synthesis of electron-rich sterically hindered P1 phosphazene bases by the staudinger reaction". . p. 1811 - 1823. Retrieved 2013/04/10.