5-ethoxy-5H-furan-2-one

Base Information

• Chemical Name: 5-ethoxy-5H-furan-2-one
• CAS No.: 2833-30-9
• Molecular Formula: C6H8O3
• Molecular Weight: 128.128
• Hs Code.: 2932209090
• European Community (EC) Number: 428-330-4,925-174-3,687-585-1
• DSSTox Substance ID: DTXSID60391143
• Nikkaji Number: J863.013E
• Mol file: 2833-30-9.mol

Synonyms:5-ethoxy-5H-furan-2-one;2833-30-9;5-Ethoxyfuran-2(5H)-one;2-ethoxy-2H-furan-5-one;EC 428-330-4;ethoxyfuranon;2(5H)-Furanone,5-ethoxy-;5-ethoxy-2,5-dihydrofuran-2-one;5-ethoxy-2(5h)-furanone;SCHEMBL981822;DTXSID60391143;NOZLVOMKFMVAKH-UHFFFAOYSA-N;AKOS006272216;SB61580;AS-76336;CS-0149690;FT-0625743;J-017047

Chemical Property of 5-ethoxy-5H-furan-2-one

Chemical Property:

• Vapor Pressure: 0.0107mmHg at 25°C
• Refractive Index: 1.465
• Boiling Point: 262.8 °C at 760 mmHg
• Flash Point: 104.3 °C
• PSA: 35.53000
• Density: 1.13 g/cm³
• LogP: 0.46200
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 128.047344113
• Heavy Atom Count: 9
• Complexity: 139

Purity/Quality:

99.9% ^*data from raw suppliers

5-Ethoxyfuran-2(5H)-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1C=CC(=O)O1

Technology Process of 5-ethoxy-5H-furan-2-one

There total 24 articles about 5-ethoxy-5H-furan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

furfural (98-01-1) + ethanol (64-17-5) → 5-ethoxy-2,5-dihydrofuran-2-one (2833-30-9)

Guidance literature:

With Eosin Y; Irradiation;

Reference yield: 15.0%

2,3,7-trioxa-bicyclo-<2.2.1>-hept-5-ene (6824-18-6) + ethanol (64-17-5) → 5-hydroxy-2-(5H)-furanone (14032-66-7) + 5-ethoxy-2,5-dihydrofuran-2-one (2833-30-9) + 3,4-epoxy-butyrolactone (82140-94-1,94739-84-1)

Guidance literature:

In chloroform; -20 deg C, then 20 deg C, 1 h;

DOI:10.1016/S0040-4020(01)96576-7

Reference yield: 2.0%

furan (110-00-9) → 5-hydroxy-2-(5H)-furanone (14032-66-7) + 5-ethoxy-2,5-dihydrofuran-2-one (2833-30-9) + 2-buten-4-olide (497-23-4) + cis-2,5-diethoxy-2,5-dihydrofuran

Guidance literature:

With oxovanadium(IV) sulfate; ethanol; dihydrogen peroxide; at 20 ℃; for 6h; Further byproducts given;

DOI:10.1007/BF02311323

upstream raw materials:

furan

ethanol

furfural

5-hydroxy-2-(5H)-furanone

Downstream raw materials:

2,4,4,7-tetramethyl-3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazine-8-carboxylic acid ethyl ester

(3aS,6R,6aR)-3-(4-Chloro-phenyl)-6-ethoxy-6,6a-dihydro-3aH-furo[3,4-d]isoxazol-4-one

(3aS,6R,6aR)-6-Ethoxy-3-(4-fluoro-phenyl)-6,6a-dihydro-3aH-furo[3,4-d]isoxazol-4-one

(3aS,6R,6aR)-6-Ethoxy-3-p-tolyl-6,6a-dihydro-3aH-furo[3,4-d]isoxazol-4-one