(S)-1-N-Boc-3-cyanopiperidine

Base Information

Chemical Name:(S)-1-N-Boc-3-cyanopiperidine
CAS No.:915226-39-0
Molecular Formula:C₁₁H₁₈N₂O₂
Molecular Weight:210.276
Hs Code.:2933399090
European Community (EC) Number:674-845-4
DSSTox Substance ID:DTXSID60426585
Wikidata:Q72448989
Mol file:915226-39-0.mol

Synonyms:915226-39-0;(S)-1-N-BOC-3-CYANOPIPERIDINE;(S)-1-N-Boc-3-Cyano-piperidine;(s)-tert-butyl 3-cyanopiperidine-1-carboxylate;tert-butyl (3S)-3-cyanopiperidine-1-carboxylate;1-piperidinecarboxylic acid, 3-cyano-, 1,1-dimethylethyl ester, (3s)-;MFCD05863903;(s)-3-cyano-piperidine-1-carboxylic acid tert-butyl ester;tert-Butyl (S)-3-cyanopiperidine-1-carboxylate;(s)-1-boc-3-cyano-piperidine;SCHEMBL1970335;(3S)-1-Boc-3-cyanopiperidine;DTXSID60426585;UEFZTXGFHKPSFS-SECBINFHSA-N;1-n-boc-3-(s)-cyano-piperidine;AMY34559;AKOS007930620;AKOS015897833;AS-45735;CS-0052938;(s)-tert-butyl-3-cyanopiperidine-1-carboxylate;B66750;Q-103086;(S)-3-Cyanopiperidine-1-carboxylic acid tert-butyl ester;(S)-tert-butyl 3-cyanopiperidine-1-carboxylate

Suppliers and Price of (S)-1-N-Boc-3-cyanopiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-tert-Butyl3-Cyanopiperidine-1-carboxylate
50mg
$ 45.00

Crysdot
(S)-1-N-Boc-3-Cyanopiperidine 97%
5g
$ 584.00

Chemenu
(S)-1-N-Boc-3-cyanopiperidine 97%
5g
$ 552.00

Biosynth Carbosynth
(S)-1-N-Boc-3-cyano-piperidine
100 mg
$ 146.00

Biosynth Carbosynth
(S)-1-N-Boc-3-cyano-piperidine
1 g
$ 881.25

Biosynth Carbosynth
(S)-1-N-Boc-3-cyano-piperidine
500 mg
$ 505.00

Biosynth Carbosynth
(S)-1-N-Boc-3-cyano-piperidine
250 mg
$ 292.50

Biosynth Carbosynth
(S)-1-N-Boc-3-cyano-piperidine
50 mg
$ 84.00

AstaTech
(S)-1-N-BOC-3-CYANO-PIPERIDINE 97%
0.25 / G
$ 102.00

AstaTech
(S)-1-N-BOC-3-CYANO-PIPERIDINE 97%
1 / G
$ 256.00

Total 27 raw suppliers

Chemical Property of (S)-1-N-Boc-3-cyanopiperidine

Chemical Property:

Vapor Pressure:0.000232mmHg at 25°C
Boiling Point:325.3°C at 760 mmHg
PKA:-3.42±0.40(Predicted)
Flash Point:150.5°C
PSA：53.33000
Density:1.07g/cm³
LogP:2.09498
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:210.136827821
Heavy Atom Count:15
Complexity:285

Purity/Quality:

97% ^*data from raw suppliers

(S)-tert-Butyl3-Cyanopiperidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC(C1)C#N
Isomeric SMILES:CC(C)(C)OC(=O)N1CCC[C@@H](C1)C#N

Technology Process of (S)-1-N-Boc-3-cyanopiperidine

There total 2 articles about (S)-1-N-Boc-3-cyanopiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 88466-77-7
(S)-3-carbamoyl-piperidine-1-carboxylic acid tert-butyl ester

: 915226-39-0
(S)-3-carbamoyl-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With pyridine; trichlorophosphate; at 0 - 20 ℃; Product distribution / selectivity;

Reference yield:

: 88495-54-9
(3S)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid

: 915226-39-0
(S)-3-carbamoyl-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: chloroformic acid ethyl ester; triethylamine / chloroform / 0.17 h / 0 °C

1.2: 4 h / 20 °C

2.1: phosphorus pentoxide / pyridine / 0 - 20 °C

With phosphorus pentoxide; chloroformic acid ethyl ester; triethylamine; In pyridine; chloroform;

Reference yield:

: 915226-39-0
(S)-3-carbamoyl-piperidine-1-carboxylic acid tert-butyl ester

: 915226-64-1
(S)-1-(4-fluoro-benzoyl)-piperidine-3-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1,4-dioxane; dichloromethane / 1.5 h / 0 - 20 °C

2: triethylamine / dichloromethane / 3 h / 0 - 20 °C

With triethylamine; In 1,4-dioxane; dichloromethane;