Technology Process of tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate
There total 5 articles about tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate;
In
dimethyl sulfoxide;
at 40 - 100 ℃;
for 2.5h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium carbonate / water; acetone / 18 h
2: N-ethyl-N,N-diisopropylamine / dichloromethane / 39 h
3: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 2.5 h / 40 - 100 °C
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; sodium carbonate; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; water; dimethyl sulfoxide; acetone;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 39 h
2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 2.5 h / 40 - 100 °C
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; dimethyl sulfoxide;
