(2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate

Base Information

Chemical Name:(2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate
CAS No.:153052-69-8
Molecular Formula:C₁₇H₂₅NO₄
Molecular Weight:307.39
Hs Code.:

Synonyms:(2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate

Suppliers and Price of (2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of (2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate

There total 6 articles about (2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 153052-68-7
(2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-2-{[(tert-butoxy)carbonyl](methyl)amino}-4-methylpentanoate

: 153052-69-8
(2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1.5h; Reagent/catalyst;

Reference yield:

: 56777-24-3
benzyl (S)-Lactate

: 153052-69-8
(2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate

Guidance literature:: Multi-step reaction with 2 steps

1: diethylazodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2: hydrogenchloride / 1,4-dioxane / 1.5 h / 20 °C

With hydrogenchloride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 1,4-dioxane;

Reference yield:

: 2051-96-9,56777-24-3,74094-05-6
benzyl (R)-Lactate

: 153052-69-8
(2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / dicyclohexylcarbodiimide, 4-dimethylaminopyridine / CH₂Cl₂ / 1.67 h / Ambient temperature

2: 89 percent / 10percent v/v trifluoroacetic acid / CH₂Cl₂ / 0.83 h

With dmap; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane;
DOI:10.7164/antibiotics.47.1322