Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester

Base Information

Chemical Name:Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester
CAS No.:161147-39-3
Molecular Formula:C₃₆H₃₇N₃O₇
Molecular Weight:623.706
Hs Code.:

Synonyms:Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester

Suppliers and Price of Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester

There total 8 articles about Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83051-88-1
methyl 6-aldehydo-2,3,4-tri-O-benzyl-α-D-glucopyranoside

: 161147-39-3
Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) n-BuLi, MgBr₂ / 1.) hexane, Et₂O, -5 deg C, 30 min, 2.) -30 deg C to r.t.

2: 74 percent / Bu₄NF / tetrahydrofuran / 0.25 h / Ambient temperature

3: 77 percent / Ph₃P, Zn(N₃)2*2py, diisopropyl azodicarboxylate / toluene / 0.5 h / Ambient temperature

4: OsO₄, aq. NaIO₄ / tetrahydrofuran / 5 h / 45 °C

5: CH₂Cl₂

With sodium periodate; osmium(VIII) oxide; n-butyllithium; zinc azide * 2 pyridine; di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; triphenylphosphine; magnesium bromide; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jo00108a030

Reference yield:

: 103597-18-8
methyl-2,3,4-tri-O-benzyl-7,7,8,8-tetradehydro-7,8-dideoxy-α-D-glycero-D-gluco-octopyranoside

: 161147-39-3
Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 77 percent / Ph₃P, Zn(N₃)2*2py, diisopropyl azodicarboxylate / toluene / 0.5 h / Ambient temperature

2: OsO₄, aq. NaIO₄ / tetrahydrofuran / 5 h / 45 °C

3: CH₂Cl₂

With sodium periodate; osmium(VIII) oxide; zinc azide * 2 pyridine; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jo00108a030

Reference yield:

: 103597-22-4
methyl-2,3,4-tri-O-benzyl-7,7,8,8-tetradehydro-7,8-dideoxy-β-L-glycero-D-gluco-octopyranoside

: 161147-39-3
Methyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-L-glycero-α-D-gluco-heptopyranosiduronic acid benzyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / Ph₃P, diethyl azodicarboxylate / tetrahydrofuran / 15 h / Ambient temperature

2: 93 percent / K₂CO₃ / methanol / 0.33 h / Ambient temperature

3: 77 percent / Ph₃P, Zn(N₃)2*2py, diisopropyl azodicarboxylate / toluene / 0.5 h / Ambient temperature

4: OsO₄, aq. NaIO₄ / tetrahydrofuran / 5 h / 45 °C

5: CH₂Cl₂

With sodium periodate; osmium(VIII) oxide; zinc azide * 2 pyridine; di-isopropyl azodicarboxylate; potassium carbonate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1021/jo00108a030