4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid

Base Information

Chemical Name:4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid
CAS No.:1239588-88-5
Molecular Formula:C₂₂H₂₃IN₂O₄S
Molecular Weight:538.406
Hs Code.:

Synonyms:4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid

Suppliers and Price of 4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid

There total 6 articles about 4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 128595-82-4
C₁₀H₁₂INO₂*ClH

: 605-65-2
5-(dimethylamino)naphth-1-ylsulfonyl chloride

: 1239588-88-5
4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid

Guidance literature:: With potassium carbonate; In water; acetonitrile; at 20 ℃; for 6h;
DOI:10.1016/j.bbrc.2010.06.120

Reference yield:

: 38239-56-4
(E)-3-(4-iodophenyl)-1-phenylprop-2-en-1-one

: 1239588-88-5
4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate / toluene / 4 h / -20 - 20 °C

2.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 48 h / 20 °C

3.1: nickel(II) chloride hexahydrate / methanol / 0.08 h / 20 °C

3.2: 0.5 h / 20 °C

4.1: hydrogenchloride; water / 18 h / 100 °C

5.1: potassium carbonate / water; acetonitrile / 6 h / 20 °C

With hydrogenchloride; nickel(II) chloride hexahydrate; N-benzyl-N,N,N-triethylammonium chloride; water; sodium hydrogencarbonate; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane; water; toluene; acetonitrile; 2.1: Baeyer-Villiger oxidation;
DOI:10.1016/j.bbrc.2010.06.120

Reference yield:

: 1239588-89-6
3-(4-iodophenyl)-4-nitro-1-phenylbutan-1-one

: 1239588-88-5
4-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(4-iodophenyl)-butanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 48 h / 20 °C

2.1: nickel(II) chloride hexahydrate / methanol / 0.08 h / 20 °C

2.2: 0.5 h / 20 °C

3.1: hydrogenchloride; water / 18 h / 100 °C

4.1: potassium carbonate / water; acetonitrile / 6 h / 20 °C

With hydrogenchloride; nickel(II) chloride hexahydrate; water; sodium hydrogencarbonate; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane; water; acetonitrile; 1.1: Baeyer-Villiger oxidation;
DOI:10.1016/j.bbrc.2010.06.120