ethyl 4-<(2'-acetylamino-4',5'-methylenedioxyphenacyl)amino>benzoate

Base Information

• Chemical Name: ethyl 4-<(2'-acetylamino-4',5'-methylenedioxyphenacyl)amino>benzoate
• CAS No.: 85590-89-2
• Molecular Formula: C₂₀H₂₀N₂O₆
• Molecular Weight: 384.389
• Mol file: 85590-89-2.mol

Synonyms:ethyl 4-<(2'-acetylamino-4',5'-methylenedioxyphenacyl)amino>benzoate

Chemical Property of ethyl 4-<(2'-acetylamino-4',5'-methylenedioxyphenacyl)amino>benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 4-<(2'-acetylamino-4',5'-methylenedioxyphenacyl)amino>benzoate

There total 5 articles about ethyl 4-<(2'-acetylamino-4',5'-methylenedioxyphenacyl)amino>benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

2'-bromoacetyl-4',5'-methylenedioxyacetanilide (85590-97-2) + p-aminoethylbenzoate (94-09-7) → ethyl 4-<(2'-acetylamino-4',5'-methylenedioxyphenacyl)amino>benzoate (85590-89-2)

Guidance literature:

In ethanol; for 3h; Heating;

Reference yield:

4-{Acetyl-[2-(6-acetylamino-benzo[1,3]dioxol-5-yl)-2-oxo-ethyl]-amino}-benzoic acid ethyl ester (85590-91-6) → ethyl 4-<(2'-acetylamino-4',5'-methylenedioxyphenacyl)amino>benzoate (85590-89-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 69 percent / 2 h / Heating

2: 78 percent / ammonia / ethanol / 5 h / 150 - 155 °C / Heating; sealed tube

3: 22.5 percent / methanolic HCl / ethanol / 6 h / Heating

4: 54 percent / ethanol / 3 h / Heating

With hydrogenchloride; ammonia; In ethanol;

Reference yield:

4-{Acetyl-[6-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,3]oxazin-(8Z)-ylidenemethyl]-amino}-benzoic acid ethyl ester (85590-92-7) → ethyl 4-<(2'-acetylamino-4',5'-methylenedioxyphenacyl)amino>benzoate (85590-89-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 78 percent / ammonia / ethanol / 5 h / 150 - 155 °C / Heating; sealed tube

2: 22.5 percent / methanolic HCl / ethanol / 6 h / Heating

3: 54 percent / ethanol / 3 h / Heating

With hydrogenchloride; ammonia; In ethanol;

upstream raw materials:

2'-bromoacetyl-4',5'-methylenedioxyacetanilide

p-aminoethylbenzoate

4-{Acetyl-[6-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,3]oxazin-(8Z)-ylidenemethyl]-amino}-benzoic acid ethyl ester

4-[Acetyl-(6-methyl-[1,3]dioxolo[4,5-g]quinazolin-8-ylmethyl)-amino]-benzoic acid ethyl ester

Downstream raw materials:

4-[(6-Methyl-[1,3]dioxolo[4,5-g]quinazolin-8-ylmethyl)-amino]-benzoic acid ethyl ester

4-[Formyl-(6-methyl-[1,3]dioxolo[4,5-g]quinazolin-8-ylmethyl)-amino]-benzoic acid ethyl ester

4-{Acetyl-[6-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,3]oxazin-(8Z)-ylidenemethyl]-amino}-benzoic acid ethyl ester

4-[Acetyl-(6-methyl-[1,3]dioxolo[4,5-g]quinazolin-8-ylmethyl)-amino]-benzoic acid ethyl ester