(methoxy-4' phenyl)-3 phenyl-3 dihydro-1,3 isobenzofurannone-1

Base Information

• Chemical Name: (methoxy-4' phenyl)-3 phenyl-3 dihydro-1,3 isobenzofurannone-1
• CAS No.: 41194-21-2
• Molecular Formula: C₂₁H₁₆O₃
• Molecular Weight: 316.356
• Mol file: 41194-21-2.mol

Synonyms:(methoxy-4' phenyl)-3 phenyl-3 dihydro-1,3 isobenzofurannone-1

Chemical Property of (methoxy-4' phenyl)-3 phenyl-3 dihydro-1,3 isobenzofurannone-1

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (methoxy-4' phenyl)-3 phenyl-3 dihydro-1,3 isobenzofurannone-1

There total 15 articles about (methoxy-4' phenyl)-3 phenyl-3 dihydro-1,3 isobenzofurannone-1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(2-(methoxymethyl)phenyl)(4-methoxyphenyl)(phenyl)methanol → (methoxy-4' phenyl)-3 phenyl-3 dihydro-1,3 isobenzofurannone-1 (41194-21-2)

Guidance literature:

With tetrabutylammomium bromide; Eosin Y; oxygen; In acetonitrile; at 20 ℃; under 760.051 Torr; Irradiation;

DOI:10.1039/d1gc02297k

Reference yield: 49.0%

o-Benzoylbenzoic acid (64693-03-4) + methoxybenzene (100-66-3) → (methoxy-4' phenyl)-3 phenyl-3 dihydro-1,3 isobenzofurannone-1 (41194-21-2)

Guidance literature:

With sulfuric acid; for 24h; Ambient temperature;

Reference yield:

o-bromobenzyl alcohol (18982-54-2) → (methoxy-4' phenyl)-3 phenyl-3 dihydro-1,3 isobenzofurannone-1 (41194-21-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.75 h / 0 °C

1.2: 2 h / 20 °C

2.1: magnesium; iodine / tetrahydrofuran / 2 h / 60 °C / Inert atmosphere

2.2: 6.33 h / 60 °C

3.1: Eosin Y; tetrabutylammomium bromide; oxygen / acetonitrile / 20 °C / 760.05 Torr / Irradiation

With tetrabutylammomium bromide; Eosin Y; iodine; oxygen; sodium hydride; magnesium; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1039/d1gc02297k

upstream raw materials:

3-chloro-3-phenylphthalide

methoxybenzene

2-(4-methoxybenzoyl)benzoic acid

2-Benzoylbenzoic acid