(2R,1'R)-N-benzyl-N-(2'-methoxy-1'-phenylethyl)-2-bromo-3-methylbutylamine

Base Information

Chemical Name:(2R,1'R)-N-benzyl-N-(2'-methoxy-1'-phenylethyl)-2-bromo-3-methylbutylamine
CAS No.:1134564-21-8
Molecular Formula:C₂₁H₂₈BrNO
Molecular Weight:390.363
Hs Code.:

Synonyms:(2R,1'R)-N-benzyl-N-(2'-methoxy-1'-phenylethyl)-2-bromo-3-methylbutylamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,1'R)-N-benzyl-N-(2'-methoxy-1'-phenylethyl)-2-bromo-3-methylbutylamine

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Technology Process of (2R,1'R)-N-benzyl-N-(2'-methoxy-1'-phenylethyl)-2-bromo-3-methylbutylamine

There total 1 articles about (2R,1'R)-N-benzyl-N-(2'-methoxy-1'-phenylethyl)-2-bromo-3-methylbutylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 100-39-0
benzyl bromide

: 514168-48-0
(S)-2-Isopropyl-1-((R)-2-methoxy-1-phenyl-ethyl)-aziridine

: 1134564-21-8
(2R,1'R)-N-benzyl-N-(2'-methoxy-1'-phenylethyl)-2-bromo-3-methylbutylamine

Guidance literature:: In acetone; at 60 ℃; for 12h; stereoselective reaction; Inert atmosphere;
DOI:10.3987/COM-08-11537

Reference yield: 93.0%

: 1134564-21-8
(2R,1'R)-N-benzyl-N-(2'-methoxy-1'-phenylethyl)-2-bromo-3-methylbutylamine

: (R)-N-benzyl-2-fluoro-N-((R)-2-methoxy-1-phenylethyl)-3-methylbutylamine

Guidance literature:: With triethylamine tris(hydrogen fluoride); In toluene; at 80 ℃; for 96h; diastereoselective reaction; Inert atmosphere;
DOI:10.3987/COM-18-S(T)58