Technology Process of C26H29N5O8
There total 17 articles about C26H29N5O8 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-hydroxy-6-methyl-benzoic acid cyanomethyl ester;
With
potassium carbonate;
In
ISOPROPYLAMIDE;
at 20 ℃;
for 1h;
Inert atmosphere;
C18H23N5O6;
In
ISOPROPYLAMIDE;
at 20 ℃;
for 0.166667h;
Inert atmosphere;
DOI:10.1002/anie.201008079
- Guidance literature:
-
C18H23N5O6; 2-hydroxy-6-methylbenzoic acid;
With
pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; dichloromethane;
at 20 ℃;
potassium cyanide;
In
methanol;
at 20 ℃;
DOI:10.1021/jo301638z
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: hydrogenchloride; water / tetrahydrofuran / 14 h / 0 - 20 °C
2.1: diisobutylaluminium hydride / dichloromethane; toluene / 2 h / -78 °C / Inert atmosphere
3.1: pyrographite; triethylamine / tetrahydrofuran / 0.25 h / -46 °C / Inert atmosphere
4.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; acetone / 2 h / 0 - 20 °C
5.1: sodium periodate / tetrahydrofuran; water / 3 h / 20 °C
6.1: tris(dimethylamino)sulfonium trimethylsilyldifluoride / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere
7.1: potassium carbonate / ISOPROPYLAMIDE / 1 h / 20 °C / Inert atmosphere
7.2: 0.17 h / 20 °C / Inert atmosphere
With
hydrogenchloride; sodium periodate; osmium(VIII) oxide; tris(dimethylamino)sulfonium trimethylsilyldifluoride; water; diisobutylaluminium hydride; potassium carbonate; pyrographite; 4-methylmorpholine N-oxide; triethylamine;
In
tetrahydrofuran; dichloromethane; ISOPROPYLAMIDE; water; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1002/anie.201008079
