p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-β-D-lyxofuranoside

Base Information

• Chemical Name: p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-β-D-lyxofuranoside
• CAS No.: 329360-43-2
• Molecular Formula: C₁₉H₁₈O₄S
• Molecular Weight: 342.416
• Mol file: 329360-43-2.mol

Synonyms:p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-β-D-lyxofuranoside

Chemical Property of p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-β-D-lyxofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-β-D-lyxofuranoside

There total 2 articles about p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-β-D-lyxofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

benzoic acid (65-85-0,8013-63-6) + p-tolyl 1-thio-β-D-arabinofuranoside → p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-β-D-lyxofuranoside (329360-43-2)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 0.75h;

DOI:10.1021/ja029302m

Reference yield: 73.0%

benzoic acid (65-85-0,8013-63-6) + (2R,3S,4S)-2-Hydroxymethyl-5-p-tolylsulfanyl-tetrahydro-furan-3,4-diol → p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-β-D-lyxofuranoside (329360-43-2) + p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-α-D-lyxofuranoside (329360-17-0)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 0.75h;

DOI:10.1021/jo001747a

Reference yield: 98.0%

p-tolyl 2,3-anhydro-5-O-benzoyl-1-thio-β-D-lyxofuranoside (329360-43-2) → p-tolyl 2,3-anhydro-1-thio-β-D-lyxofuranoside

Guidance literature:

With sodium methylate; In methanol; dichloromethane; at 20 ℃;

DOI:10.1021/jo001747a

upstream raw materials:

benzoic acid

Downstream raw materials:

n-octyl 2,3-anhydro-5-O-benzoyl-β-D-lyxofuranoside

5-O-benzoyl-2-deoxy-2-(p-thiotolyl)-α-D-arabinofuranosyl azide

5-O-benzoyl-2-deoxy-2-(p-thiotolyl)-3-O-(5-O-benzoyl-2-deoxy-2-(p-thiotolyl)-α-D-arabino-furanosyl)-α-D-arabinofuranosyl azide

(1R,5R,7R,8R)-7-benzoyloxymethyl-8-(thiotolyl)-3-(R/S)-((trimethylsilyl)methyl)-2,6-dioxabicyclo[3.2.1]octane