4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine

Base Information

Chemical Name:4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine
CAS No.:175357-96-7
Molecular Formula:C₁₃H₁₀BrN₅
Molecular Weight:316.16
Hs Code.:
DSSTox Substance ID:DTXSID701215207
Nikkaji Number:J746.176C
Pharos Ligand ID:9WNLUGRKZW5W
ChEMBL ID:CHEMBL51853

Synonyms:CHEMBL51853;Pyrido[3,4-d]pyrimidine 7b;BDBM3600;SCHEMBL2764474;TWTYLCVLKNHZDT-UHFFFAOYSA-;4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine;TWTYLCVLKNHZDT-UHFFFAOYSA-N;DTXSID701215207;175357-96-7;N-(3-Bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine;N4-(3-Bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine;6-amino-4-[(3-bromophenyl)-amino]pyrido[3,4-d]pyrimidine;6-amino-4-[(3-bromophenyl)amino]-pyrido[3,4-d]pyrimidine;6-amino-4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidine;InChI=1/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-5-12(15)16-6-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)

Suppliers and Price of 4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:315.01196
Heavy Atom Count:19
Complexity:303

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Br)NC2=NC=NC3=CN=C(C=C32)N

Technology Process of 4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine

There total 5 articles about 4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 175357-97-8
4-[(3-bromophenyl)-amino]-6-[(4-methoxyphenyl)-methylamino]pyrido[3,4-d]pyrimidine

: 175357-96-7
6-amino-4-[(3-bromophenyl)-amino]pyrido[3,4-d]pyrimidine

Guidance literature:: With trifluoroacetic acid; for 1h; Heating;
DOI:10.1021/jm9508651

Reference yield:

: 591-19-5
m-Bromoaniline

: 175357-96-7
6-amino-4-[(3-bromophenyl)-amino]pyrido[3,4-d]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / propan-2-ol / 0.25 h / Heating

2: 28 percent / ethanol / 120 h / 100 °C

3: 55 percent / TFA / 1 h / Heating

With trifluoroacetic acid; In ethanol; isopropyl alcohol;
DOI:10.1021/jm9508651

Reference yield:

: 175357-98-9
4-chloro-6-fluoro-pyrido[3,4-d]pyrimidine

: 175357-96-7
6-amino-4-[(3-bromophenyl)-amino]pyrido[3,4-d]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / propan-2-ol / 0.25 h / Heating

2: 28 percent / ethanol / 120 h / 100 °C

3: 55 percent / TFA / 1 h / Heating

With trifluoroacetic acid; In ethanol; isopropyl alcohol;
DOI:10.1021/jm9508651